High level of ezrin expression in colorectal cancer tissues is closely related to tumor malignancy

Table 1 Ezrin expression in different colorectal tissues n (%)

Group	n	Positive expression (%)
Normal colorectal mucosa	22	2 (9.09)b
Colorectal cancer tissues	80	60 (75.00)

^bP < 0.01 vs colorectal cancer tissues.

Table 2 Relationship between ezrin expression in colorectal cancer tissues and clinicopathological parameters n (%)

Clinicopathological parameters	n	Ezrin positive expression (%)
Well-differentiated	28	14 (50.00)b
Moderately and poorly differentiated	52	46 (88.46)
Lymph node metastasis	35	33 (94.28)d
Without lymph node metastasis	45	27 (51.11)
Dukes A to B stage	45	27 (51.11)e
Dukes C to D stage	35	33 (94.28)

There was a close relationship between ezrin expression and the degree of tumor differentiation, lymph node metastasis and Dukes stage. There were significant differences between the well-differentiated and the moderately and poorly differentiated groups (^bP < 0.01); lymph node metastasis group vs group without lymph node metastasis (^dP < 0.01); Dukes A to B stage vs Dukes C to D stage (^eP < 0.01).