Brief Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Mar 28, 2009; 15(12): 1487-1492
Published online Mar 28, 2009. doi: 10.3748/wjg.15.1487
Table 1 Characteristics of the study population
HospitalNumber of the subjectsType of CT colonogrphykVpmAsPitchSlice thickness/reconstruction intervalfor extracolonic finding (mm)
A278Sensation 64; Siemens, Erlangen, Germany120701.53/3
B157LightSpeed Ultra 8 or 16; GE Medical systems, Milwaukee, WI120701.351.25/1.25
C152Sensation 16; Siemens, Erlangen, Germany1203015/5
D135Brilliance 40-channel MDCT, Phillips Medical System, Netherlands1201601.1760.5/0.9
E92LightSpeed 16; GE healthcare, Milwaukee, Wis1202001.3751.25/3.75
F65MX 8000 IDT 16, Phillips Eindhoven, Netherlands12020012/1
G41Sensation 16; Siemens, Erlangen, Germany1203015/5
Table 2 Results of 920 computed tomographic colonoscopy examinations n (%)
Number of extracolonic findingsNumber of subjects
0388 (42.2)
1403 (43.8)
2105 (11.4)
319 (2.1)
45 (0.5)
Table 3 Proportion of extracolonic lesions according to the clinical significance
Extracolonic findingsNumber
Highly significant (n = 60)
Solid organ mass including malignancy421
Cardiomegaly/pericardial effusion5
Lymphadenopathy greater than 1 cm3
Peritoneal carcinomatosis3
Abscess3
Aortic lesion2
Small bowel obstruction2
Intermediately significant (n = 250)
Benign solid organ lesion1412
Renal stone/hydronephrosis28
Gall bladder stone/polyp/cholecystitis22
Liver cirrhosis13
Bile duct stone/dilatation/hemobilia9
Small bowel inflammation8
Vascular lesion (aortic stenosis, varix, etc)6
Bronchiectasis/emphysema5
Hepatosplenomegaly5
Pleural effusion3
Inguinal hernia3
Ascites of unknown cause3
Chronic pancreatitis2
Mesenteric fat necrosis1
Spinal stenosis with destruction1
Lowly significant (n = 382)
Renal cyst143
Hepatic cyst114
Fatty liver39
Vascular calcification/atherosclerosis19
Chronic pulmonary disease/pleural thickening16
Accessory spleen/splenic infarction15
Hepatic calcification10
Benign osteolytic lesion8
Hiatal hernia6
Benign prostatic hypertrophy5
Colonic diveticulosis4
Tiny pancreas cyst1
Mesenteric calcification1
Gallbladder sludge1
Table 4 Baseline characteristics according to the clinical significance of extracolonic lesions n (%)
Highly significant lesion (n = 60)Intermediately significant lesion (n = 250)Lowly significant lesion (n = 382)No extracolonic lesion (n = 388)P-value
Age (mean ± SD)58.3 ± 16.457.9 ± 13.859.0 ± 11.954.4 ± 13.1< 0.001
Male:Female36:24116:134237:145233:1550.001
Indication< 0.001
Screening16 (26.7)76 (30.4)155 (40.6)160 (41.2)
Family history1 (1.7)4 (1.6)4 (1.0)13 (3.4)
Past history10 (16.7)38 (15.2)55 (14.4)93 (24.0)
GI bleeding5 (8.3)19 (7.6)11 (2.9)17 (4.4)
IDA1 (1.7)7 (2.8)8 (2.1)0 (0.0)
Bowel habit change6 (10.0)27 (10.8)44 (11.5)38 (9.8)
Abdominal pain17 (28.2)58 (23.2)78 (20.4)56 (14.4)
Others4 (6.7)21 (8.4)27 (7.1)11 (2.8)
CT with enhancement153 (88.3)225 (90.0)320 (83.7)305 (78.6)0.001
Hospital< 0.001
A (n = 313)23 (38.4)61 (24.4)77 (20.2)151 (38.9)
B (n = 214)9 (15.0)86 (34.4)86 (22.6)33 (8.5)
C (n = 171)5 (8.3)24 (9.6)60 (15.7)81 (20.9)
D (n = 149)2 (3.3)31 (12.4)70 (18.3)45 (11.6)
E (n = 104)10 (16.7)20 (8.0)44 (11.5)30 (7.7)
F (n = 73)5 (8.3)16 (6.4)12 (3.1)40 (10.3)
G (n = 59)6 (10.0)12 (4.8)33 (8.6)8 (2.1)
Table 5 Further managements according to the clinical significance of extracolonic lesions n (%)
Highly significant lesion (n = 60)Intermediately significant lesion (n = 250)Lowly significant lesion (n = 382)
Diagnostic intervention
US6 (10.0)108 (43.2)31 (8.1)
CT17 (28.3)65 (26.0)21 (5.5)
MRI4 (6.7)14 (5.6)0 (0.0)
Biopsy8 (13.3)3 (1.2)2 (0.5)
Endoscopy6 (10.0)6 (2.4)1 (0.3)
Other tests18 (30.0)25 (10.0)10 (2.6)
Not done1 (1.7)29 (11.6)317 (83.0)
Therapeutic intervention49 (81.7)52 (20.8)11 (2.9)