Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)

Table 1 The use of different scolicidal agents at the 5th and 10th min for the treatment of hydatid disease (in vitro results)

Time	NaCl 20%	H2O2	Cetrimide	Sulfone	Sulfoxide	Sulfone + Sulfoxide
5th min	98.2%	90.3%	86.9%	97.3%	98.4%	98.6%
10th min	99.5%	95.7%	92.6%	98.6%	99.5%	99.6%

Table 2 Different scolicidal agents in literature

Author	Agents	Results
Caglar et al[26] (2008)	20% silver nitra (20 min)	100% death
	50% Dextroz (30 min)	100% death
	20% NaCl (45 min)	100% death
	20% Mannitol (45 min)	100% death
Frayha et al[27] (1981)	Cetrimide 0.5%-1% (10 min)	100% death
Kayaalp et al[28] (2002)	10%-30% NaCl (3, 6, 75 min	100% death
Sonişik et al[11] (2002)	10%-30% NaCl ( 3, 6 and 75 min)	100% death
Besim et al[16] (1989)	20% Saline (15 min)	100% death
	95% Ethyl alcohol (15 min)	100% death
	10% Polyvinyl pirrolidone iodine (15 min)	100% death
	3% H2O2 (15 min)	100% death
Erzurumlu et al[20] (1998)	Albendazole sulfoxide 20 &mgr;g/mL	5% death
	Albendazole sulfoxide 50 &mgr;g/mL	50% death
	Albendazole sulfoxide 100 &mgr;g/mL	100% death
Adas et al (our study)	20% NaCL (5 min)	98.2% death
(2008)	3% H2O2 (5 min)	90.3% death
	Cetrimide (5 min)	86.9% death
	Albendazole sulfone (5 min)	97.3% death