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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 7, 2008; 14(9): 1419-1424
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1419
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1419
Table 1 Effects of GHS-R agonists on the spontaneous contractile amplitudes of DM mouse fundic strips
Group | Spontaneous contractile amplitude of DM mouse fundic strips (mg) | ||||
0 | 0.01&mgr;mol/L | 0.1&mgr;mol/L | 1&mgr;mol/L | 10&mgr;mol/L | |
Ghrelin | 20.4 ± 1.15 | 21.3 ± 0.98 | 19.8 ± 1.16 | 22.1 ± 1.58 | 21.5 ± 1.36 |
GHRP-6 | 20.4 ± 1.15 | 20.8 ± 1.12 | 21.3 ± 1.74 | 20.6 ± 1.27 | 21.3 ± 1.35 |
Table 2 Effect of GHS-R agonists on the carbachol (0.1 &mgr;mol/L)-induced contractile amplitudes of DM mouse fundic strips
Group | Spontaneous contractile amplitude of DM mouse fundic strips (mg) | ||||
0 | 0.01&mgr;mol/L | 0.1&mgr;molL | 1&mgr;mol/L | 10&mgr;mol/L | |
Ghrelin + carbachol (0.1 &mgr;mol/L) | 60.4 ± 1.21 | 61.3 ± 1.52 | 65.7 ± 1.16a | 70.0 ± 1.58a | 78.0 ± 1.56a |
GHRP-6 + carbachol (0.1 &mgr;mol/L) | 60.4 ± 1.21 | 62.3 ± 2.14 | 65.4 ± 1.24a | 72.0 ± 1.42a | 82.0 ± 1.75a |
- Citation: Qiu WC, Wang ZG, Wang WG, Yan J, Zheng Q. Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis. World J Gastroenterol 2008; 14(9): 1419-1424
- URL: https://www.wjgnet.com/1007-9327/full/v14/i9/1419.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.1419