Endoscopic transpapillary brush cytology and forceps biopsy in patients with hilar cholangiocarcinoma

Table 1 Patients characteristics, physical and laboratory parameters on admission

	Patient characteristics	Standart values	Scale unit
Number of patients	58	-	-
Gender	Male (m): 31 (53.4%)	-	-
	Female (f): 7 (46.6%)	-	-
Bismuth II	7	-	-
Bismuth III	25	-	-
Bismuth IV	26	-	-
Bilirubin	6.9 ± 7.6	< 1.2	mg/dL
Alkaline phosphatase	559 ± 270	40-120	U/L
γ-GT	404 ± 362	< 66	U/L
Leucocytes	8.8 ± 3.8	4-9	G/L

Table 2 Number of tissue sampling sessions

Number of tissue sampling sessions	Number of patients	Number of samples
1 session	47	47
2 sessions	8	16
3 sessions	2	6
4 sessions	1	4
	58	73

Table 3 Sensitivity of brush cytology and forceps biopsy in patients with hilar cholangiocarcinoma n (%)

	Positive for malignancy
Brush cytology	24/731 (32.9)
	24/582 (41.4)
Forceps biopsy	31/731 (42.5)
	31/582 (53.4)
Combination of cytology and biopsy	35/731 (47.9)
	35/582 (60.3)

¹Samples;

²Patients.

Table 4 True positive and false negative results for cytological and histological investigation

	Histology positive		Histology negative		Total
	Samples	Patients	Samples	Patients	Samples	Patients
Cytology positive	20	20	4	4	24	24
Cytology negative	11	11	38	23	49	34
Total	31	31	42	27	73	58