Non-alcoholic fatty liver disease in the Philippines: Comparable with other nations?

Table 1 Distribution of BMI n (%)

Gender	Underweight	Normal	Overweight	Obese
Female	10 (11%)	5 (6%)	8 (9%)	64 (74%)
Male	17 (36%)	10 (21%)	4 (9%)	16 (34%)
Total	27 (20%)	15 (11%)	12 (9%)	80 (60%)

Table 2 Laboratory characteristics of NAFLD patients at the Philippine General Hospital

Parameter	Blood chemistry values
	Total n = 134 (mean)	Male n = 39 (mean)	Female n = 95 (mean)
Liver weight (g)	1722 ± 488	1505 ± 399	1952 ± 512
AST (U/L) n (15-137)	150 ± 19	164 ± 27	112 ± 20
ALT (U/L) n (30-65)	192 ± 17	187 ± 24	217 ± 18
Alkaline phosphatase (g/dL) n (50-136)	89 ± 20	87 ± 30	92 ± 22
Albumin (g/L) n (34-50)	33.5 ± 6	35 ± 8	32 ± 6
Prothrombin time (PT) INR	1.1 ± 1	0.95 ± 1	1.2 ± 1
	Median (range)	Median (range)	Median (range)
PT activity %	88 (79-99)	90 (79-99)	88 (90-97)
Partial thromboplastin time (s)	30.1 (28-49.1)	32 (28-40.3)	34.6 (33-49.1)
Random blood sugar mmol/L n (3.9-6.1)	8.3 (4.9-20.1)	7.6 (5.5-20.1)	8.3(4.9-18.2)

Table 3 Comparison between studies of the characteristic features of NAFLD patients

Study	No. of patients	Age (yr)	Female (%)	Diabetes (%)	Obesity (%)	Hepatomegaly (%)
Ludwig (1988)18	20	54	65	50	90	67
Diehl (1988)28	39	52	81	55	71	20
Lee (1989)25	49	53	78	51	69	-
Powell (1990)26	42	49	83	36	95	81
Bacon (1994)27	33	47	42	21	39	21
Matteoni (1999)29	132	53	53	33	70	92
Khurram (2003)31	50	47	54	44	66	76
Our study (2005)	134	42	71	69	60	56