A subset of ulcerative colitis with positive proteinase-3 antineutrophil cytoplasmic antibody

Table 1 Demographic data of the five patients

Case	Gender	Age (yr)	Date of admission1	Date of initial diagnosis
1	Female	57	Dec 2006	Nov 2006
2	Female	48	Feb 2007	Jun 2006
3	Male	67	Jun 2007	May 2007
4	Female	33	May 2006	May 2004
5	Male	55	Jul 2007	May 2007

¹Patients were admitted to Division of Gastroenterology, Shanghai Renji Hospital.

Table 2 Common manifestations of disease in the five patients

Case	Bloody diarrhea	Abdominal pain	Relapse	Activity	Colonoscopy	Histological examination	Other colorectal inflammation
1	20 times/d	Yes	Yes	Severe	Entire colorectum erosion, ulcer	Mucosa inflammatory	No
2	4 times/d	Yes	Yes	Moderate	Entire colorectum erosion, ulcer	Mucosa inflammatory	No
3	6 times/d	Yes	Yes	Severe	Entire colorectum erosion, ulcer	Mucosa inflammatory	No
4	7 times/d	Yes	Yes	Severe	Entire colorectum erosion, ulcer	Mucosa inflammatory	No
5	5 times/d	Yes	No	Moderate	Entire colorectum erosion	Mucosa inflammatory	No

Table 3 Treatment of the five patients

Case	Induction of remission	Immunosuppressant		Maintenance of remission
		Azathioprine	Cyclophosphamide
1	Methylprednisolone 40 mg/d, iv	50 mg/d, po	0.6 g, iv	Colectomy
2	Methylprednisolone 40 mg/d, iv			Chinese medicine compound
	Chinese medicine compound
3	Methylprednisolone 40mg/d, iv + prednisone 20 mg/d, po	50 mg/d, po	0.6 g, iv	Chinese medicine compound
	Chinese medicine compound
4	Methylprednisolone 40 mg/d or 80mg/d, iv	50 mg/d, po	0.6 g, iv	Chinese medicine compound
5	Methylprednisolone 40 mg/d, iv			Sulphasalazine 2 g/d