Surgical outcome of adenosquamous carcinoma of the pancreas

Table 1 Clinical and pathological data for the 39 cases that underwent surgical resection for adenosquamous carcinoma of the pancreas

Author	Ref	Yr	Age	Sex	Location	Surgery	Size (cm)	Cx	RT	Rec site	Survival
Ishikawa	7	1980	67	M	Body	DP	10.0	-	-	Widespread metastasis	4 mo
			53	F	Head	PD	4.2	-	-		2 d
			61	M	Head	PD	4.5	-	-		12 mo
Wilczynski	8	1984	68	M	Head, body	PD	4.5	-	-		20 d
Yamaguchi	9	1991	60	M	Head	PD	ND	-	-	ND	3 mo
			52	F	Head	PD	ND	-	-	ND	7 mo
			44	F	Head	PD	ND	-	-	ND	5 mo
			56	F	Head	PD	ND	-	-	ND	4 mo
			56	M	Head	PD	ND	-	-	ND	5 mo1
			68	F	Head	PD	ND	-	-	ND	5 mo1
			49	F	Body	DP	ND	-	-	ND	5 mo
			61	M	Tail	DP	ND	-	-	ND	14 mo1
Motojima	10	1992	52	M	Body, tail	DP	7.0	ND	ND	Systemic metastasis	3 mo
			75	M	Head	PD	3.0	ND	ND	Liver	10 mo
			75	F	Head	PD	6.0	ND	ND	Liver	8 mo
Tanaka	11	1994	48	F	Head	PD	4.2	+	-	ND	7 mo
Makiyama	12	1995	58	M	Head	PD	5.0	-	-	Peritoneum	18 mo
Onoda	13	1995	64	M	Body, tail	DP	7.0	+	-	Liver, peritoneum	3 mo
Campman	14	1997	65	F	Body, tail	DP	7.5	ND	ND	ND	ND
Kuji	15	1997	73	M	Body, tail	TP	6.0	-	-	ND	2 mo
Nabae	16	1998	60	M	Body	DP	6.0	-	IOR	ND	4 mo
			73	M	Head	PD	ND	-	-	Liver	10 mo
Myung	17	1998	64	M	Head	PD	3.5	-	-	ND	4 mo1
Lozano	18	1998	75	M	Head, body	PD	4.5	+	+	ND	ND1
			42	M	Head	PD	3.5	+	+	ND	ND1
Aranha	19	1999	52	M	Head	PD	3.2	+	+	Systemic metastasis	13 mo
			62	M	Head	PD	3.0	+	+	Systemic metastasis	14 mo
Komatsuda	20	2000	67	M	Body	DP	5.0	-	-	Peritoneum	6 mo
Yavus	21	2000	51	M	Head	PD	4.0	ND	ND	-	36 mo1
			48	M	Head	PD	2.0	ND	ND	ND	ND
Yamaue	22	2001	63	F	Head	PD	4.5	+	+	-	40 mo1
Kardon	23	2001	ND	ND	Head	PD	ND	-	-	ND	33 mo1
Murakami	24	2003	41	M	Head	PD	3.0	-	+	Peritoneum	5 mo
Rahemtullah	25	2003	ND	ND	Head	PD	ND	ND	ND	ND	13 mo1
			ND	ND	Head	PD	ND	ND	ND	ND	ND
Alwaheeb	26	2005	45	M	Head	PD	6.0	-	-	ND	ND
Hsu	27	2005	66	M	Head	PD	3.5	-	-	ND	2.5 mo
			38	F	Head	PD	3.8	-	+	ND	6.8 mo
Jamali	28	2007	75	M	Head	PD	3.0	+	-	Liver	6 mo

Cx: Chemotherapy; RT: Radiotherapy; Rec site: Recurrence site; ND: Not described; PD: Pancreaticoduodenectomy; DP: Distal pancreatectomy; TP: Total pancreatectomy.

¹Surviving patients.

Table 2 Clinical characteristics after surgical resection for adenosquamous carcinoma of the pancreas

Characteristics	No. of patients	Survival rate (%)			Median survival in months (range)	P value
		1 yr	2 yr	3 yr
Overall	39	25.5	14.0	14.0	6.8 (4.6-9.0)
Age (yr)
< 60	16	26.9	9.0	9.0	6.8 (4.4-9.2)	0.975
> 60	20	20.4	13.6	13.6	6.0 (1.3-10.7)
Gender
Male	25	28.4	8.5	8.5	6.0 (1.1-10.9)	0.842
Female	11	12.0	12.0	12.0	6.8 (5.0-8.6)
Tumor location
Head	30	34.8	17.9	17.9	8.0 (5.3-10.7)	0.017
Body or tail	9	11.1	-	-	4.0 (2.6-5.4)
Operation type
PD	30	33.4	17.2	17.2	8.0 (5.2-10.8)	0.063
DP or TP	9	12.5	-	-	4.0 (2.7-5.3)
LN metastasis
Present	14	20.0	-	-	5.0 (2.0-8.0)	0.134
Absent	8	50.0	50.0	50.0	5
Chemotherapy
Yes	8	50.0	16.7	16.7	7.0 (0.0-15.4)	0.364
No	23	18.4	9.2	-	5.0 (3.0-7.0)
Radiotherapy
Yes	7	60.0	20.0	20.0	13.0 (0.0-26.3)	0.284
No	23	18.0	9.0	-	6.0 (4.0-8.0)

PD: Pancreaticoduodenectomy; DP: Distal pancreatectomy; TP: Total pancreatectomy; LN metastasis: Lymph node metastasis.