Vagenas K, Panagiotopoulos S, Kehagias I, Karamanakos SN, Mead N, Kalfarentzos F. Prospective evaluation of laparoscopic Roux en Y gastric bypass in patients with clinically severe obesity. World J Gastroenterol 2008; 14(39): 6024-6029 [PMID: 18932281 DOI: 10.3748/wjg.14.6024]
Corresponding Author of This Article
Fotis Kalfarentzos, MD, FACS, Professor and Chairman, Department of Surgery, School of Medicine, University of Patras, Platia Voriou Ipirou 5, Patras 26441, Greece. fkalfar@med.upatras.gr
Article-Type of This Article
Rapid Communication
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World J Gastroenterol. Oct 21, 2008; 14(39): 6024-6029 Published online Oct 21, 2008. doi: 10.3748/wjg.14.6024
Table 1 Patients’ preoperative characteristics
Period of study
September 2003 to June 2008
Number of patients
130
Male:Female
21:109
Age (yr)
37 ± 9.4 (18-55)
Weight (kg)
125 ± 13.4 (95-170)
Excess weight (kg)
65 ± 9.7 (39-103)
% EBW
208 ± 14.5 (160.9-253.7)
ΒΜΙ (kg/m2)
46 ± 3.0 (37.5-50)
Table 2 Preoperative comorbidities
Comorbidities
No. of patients (%)
Hypertension
21 (16.3)
COPD
22 (17.0)
Sleep apnea
13 (10.0)
Osteoarthritis
21 (16.3)
Depression
11 (8.5)
Diabetes Mellitus
24 (18.6)
OGTT
8 (6.2)
Hypercholesterolemia
64 (49.6)
Hypertriglyceridemia
36 (27.9)
Table 3 Incidence of postoperative complications and management
Time
Complications
Treatment
% of patients
Early < 30 d
3 gastrointestinal hemorrhages
Conservative (2)
2.4
Operation (1)
2 enterocutaneous fistulas
Operation
1.6
1 peritonitis
Operation, ICU admission
0.8
1 ileus due to volvulus
Operation
0.8
1 portal vein thrombosis
Anticoagulants
0.8
1 wound infection of port site
Antibiotics
0.8
2 orthopedic injuries
Immobilization
1.6
1 atelectasis
Antibiotics peros
0.8
No incisional hernia
0.0
1 anastomotic leak
Conservative
0.8
Intermediate 30-90 d
1 incisional hernia
No operation
0.8
Late > 90 d
5 incisional hernias
Operation (4)
3.9
4 episodes of ileus
Operation (1)
3.1
Conservative (3)
1 suicide attempt
0.8
1 gastrojejunal anastomosis stenosis
Endoscopic dilatation
0.8
Table 4 Weight loss during follow-up
0 mo
12 mo
24 mo
36 mo
48 mo
Patients
130
110
85
51
16
Weight (kg)
125
81.6
81.4
84.1
79.2
BMI
46
30
31
32
31
IWL %
34.2
34.3
32.2
31.4
EWL %
66.2
65.9
61.5
61.1
Pts > 50% EWL
92
68
35
12
Table 5 Postoperative resolution of comorbidities
Comorbidities
No. of patients
Follow- up period (mo)
Resolved (%)
Improved (%)
Without change (%)
Hypertension
21
24
84
16
COPD
22
12
100
Sleep apnea
13
12
100
Osteoarthritis
21
12
100
Depression
11
24
89
11
Diabetes Mellitus
24
12
91.7
8.3
OGTT
8
12
100
Hypercholesterolemia
64
36
94.4
5.6
Hypertriglyceridemia
36
12
100
Citation: Vagenas K, Panagiotopoulos S, Kehagias I, Karamanakos SN, Mead N, Kalfarentzos F. Prospective evaluation of laparoscopic Roux en Y gastric bypass in patients with clinically severe obesity. World J Gastroenterol 2008; 14(39): 6024-6029