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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Oct 7, 2008; 14(37): 5674-5682
Published online Oct 7, 2008. doi: 10.3748/wjg.14.5674
Published online Oct 7, 2008. doi: 10.3748/wjg.14.5674
Table 1 MHC-I binding predictions of 144-183 residue of HbcAg, processed by the SMM method
Allele | Position (aa) | Pep length | Sequence | IC50 (nm)1 |
HLA A*3101 | 148-157 | 10 | VVRRRGRSPR | 30.9 |
HLA A*3101 | 150-159 | 10 | RRRGRSPRRR | 13.7 |
HLA A*3101 | 157-166 | 10 | RRRTPSPRRR | 19.2 |
HLA A*3101 | 159-167 | 9 | RTPSPRRRR | 38.4 |
HLA A*3101 | 165-174 | 10 | RRRSQSPRRR | 19.2 |
HLA A*3101 | 166-175 | 10 | RRSQSPRRRR | 35.4 |
HLA A*3101 | 167-175 | 9 | RSQSPRRRR | 13.7 |
HLA A*3201 | 159-167 | 9 | RTPSPRRRR | 48.6 |
HLA A*6801 | 145-154 | 9 | ETTVVRRRGR | 23 |
HLA A*6801 | 146-154 | 9 | TTVVRRRGR | 22.3 |
HLA B*0702 | 162-170 | 9 | SPRRRRSQS | 21.3 |
HLA B*0702 | 170-178 | 9 | SPRRRRSQS | 21.3 |
HLA B*0702 | 155-163 | 9 | SPRRRTPSP | 40.4 |
HLA B*0801 | 162-170 | 9 | SPRRRRSQS | 39.5 |
HLA B*0801 | 170-178 | 9 | SPRRRRSQS | 39.5 |
HLA B*2705 | 150-159 | 10 | RRRGRSPRRR | 49.5 |
HLA B*2705 | 164-173 | 10 | RRRRSQSPRR | 14.7 |
HLA B*2705 | 166-175 | 10 | RRSQSPRRRR | 33.9 |
Table 2 Deletion of aa 1-11 in preS1 in the different HBV genotypes
Genotype | GenBank No. | Clinic status | Countries/district | Ref. |
Human | ||||
Genotype C | AF223959 | CHB | Vietnam | Erik et al, 2001 |
AY217372 | CHB | China | Luo et al, 2004 | |
AB195945 | CHB | Japan | Horiike et al, 2007 | |
EF533714 | HCC | China | 1Gao et al, 2007 | |
AY206389 | HCC | China | 1Lin et al, 2002 | |
AB014395 | HCC | Japan | Takahashik et al, 1998 | |
AY641563 | HCC | South Korea | Song et al, 2005 | |
D1666 | AHB | Japan | Uchida et al, 1995 | |
X98076 | FHB | Switzerland | Pult et al, 1997 | |
Genotype D | AB033559 | CHB | Papua New Guinea | Okamoto et al, 1988 |
AB119256 | CHB | Japan | Michitaka et al, 2006 | |
M32138 | Anti-HBe | France | Tong et al, 1990 | |
AY902777 | FHB | Montana | Garfein et al, 2004 | |
Genotype A | AF297621 | FHB | Africa | Owiredu et al, 2001 |
U87743 | AHB | South Africa | Bowyer et al, 1997 | |
X69458 | AHB | Zimbabwe | Chirara et al, 1994 | |
Ape | ||||
Gibbon | AB037928 | East Asia | Aiba et al, 2003 | |
Chimpanzee | D00220 | HBsAg (+) | London | Vaudin et al, 1988 |
Gorila | AJ131567 | HBsAg (+) | Japan | Grethe et al, 2000 |
Orangutan | AF193864 | CHB | Bornean | Verschoor et al, 2001 |
Recombination | ||||
Human-Gibbon | AB048705 | HBsAg (+) | Australian Aborigines | Sugauchi et al, 2001 |
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Citation: Shen T, Yan XM, Zou YL, Gao JM, Dong H. Virologic characteristics of hepatitis B virus in patients infected
via maternal-fetal transmission. World J Gastroenterol 2008; 14(37): 5674-5682 - URL: https://www.wjgnet.com/1007-9327/full/v14/i37/5674.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.5674