Laryngopharyngeal reflux in patients with reflux esophagitis

Table 1 Demographic characteristics of 167 patients

Demographic characteristics	n
Gender (male/female)	80/87
Age (yr)
mean ± SD	48.8 ± 12.8
Range	21- 81
BMI (kg/m2)
mean ± SD	23.4 ± 3.2
Range	16.1-36.3
LPR symptoms (%)
Hoarseness	56 (33.5)
Globus	56 (33.5)
Cough	46 (27.5)
Throat clearing	59 (35.3)
LA grade (%)
A	118 (70.7)
B	43 (25.7)
C	6 (3.6)
Hiatus hernia (%)	23 (13.8)

BMI: Body mass index; LPR: Laryngopharyngeal reflux; LA grade: The grade of Los Angeles classification of esophagitis.

Table 2 Comparisons of demographic characteristics of patients with and without LPR

	LPR (n = 40)	Non-LPR (n = 127)	P
Gender (%)			0.67
Male	18 (45.0)	62 (48.8)
Female	22 (55.0)	65 (51.2)
Age (yr)	45.2 ± 11.9	49.9 ± 12.9	0.04
BMI (kg/m2)	23.3 ± 3.2	23.4 ± 3.2	0.88
LPR symptoms (%)
Hoarseness	22 (55.0)	34 (26.8)	0.001
Globus	14 (35.0)	42 (33.1)	0.82
Cough	12 (30.0)	34 (26.8)	0.69
Throat clearing	16 (40.0)	43 (33.9)	0.47
LA grade (%)			0.68
A	29 (72.5)	89 (70.1)
B	9 (22.5)	34 (26.8)
C	2 (5.0)	4 (3.1)
Hiatus hernia (n, %)	11 (27.5)	12 (9.5)	0.004

BMI: Body mass index; LPR: Laryngopharyngeal reflux; LA grade: The grade of Los Angeles classification of esophagitis.

Table 3 Logistic regression analyses on predictors of LPR

	Odds ratio
	Model 1	Model 2
Gender
Female	-	-
Male	0.72	0.82
Age	0.961	0.961
BMI	0.98	0.99
LPR symptoms
Hoarseness	4.121	-
Globus	1.77	1.21
Cough	0.91	1.23
Throat clearing	0.82	1.24
LA grade
A	-	-
B	0.81	0.76
C	2.35	2.21
Hiatus hernia	4.781	-
Hiatus hernia and Hoarseness	-	12.31

BMI: Body mass index; LPR: Laryngopharyngeal reflux; LA grade: The grade of Los Angeles classification of esophagitis.

¹P value is significant at the 0.05 level.