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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jul 7, 2008; 14(25): 4082-4086
Published online Jul 7, 2008. doi: 10.3748/wjg.14.4082
Published online Jul 7, 2008. doi: 10.3748/wjg.14.4082
Table 1 Sequential change of positive rate of serum p53-Abs in EC patients before and after radiotherapy
Table 2 Relationship between positive rate of serum p53-Abs and clinical pathophysiological characteristics in EC patients
n | - | + | Positive (%) | χ2 | P | |
Age (yr) | 0.27 | 0.870 | ||||
< 50 | 16 | 10 | 6 | 37.5 | ||
≥ 50 | 30 | 18 | 12 | 40.0 | ||
Sex | 0.11 | 0.918 | ||||
Male | 38 | 23 | 15 | 39.5 | ||
Female | 8 | 5 | 3 | 37.5 | ||
TNM stage | 6.09 | 0.014 | ||||
I+ II | 27 | 21 | 6 | 22.2 | ||
III + IV | 19 | 8 | 11 | 57.9 | ||
Histological grade | 10.43 | 0.002 | ||||
I | 15 | 13 | 2 | 13.3 | ||
II | 17 | 11 | 6 | 35.3 | ||
III | 14 | 4 | 10 | 71.4 | ||
Lymph node metastasis | 6.00 | 0.015 | ||||
Positive | 18 | 7 | 11 | 61.1 | ||
Negative | 28 | 21 | 7 | 25.0 | ||
Size of tumor | 2.74 | 0.102 | ||||
< 6 cm | 32 | 22 | 10 | 31.3 | ||
≥ 6 cm | 14 | 6 | 8 | 57.1 | ||
Site of the tumor | 0.02 | 0.953 | ||||
Upper thorax | 5 | 3 | 2 | 40.0 | ||
Middle thorax | 21 | 13 | 8 | 38.1 | ||
Lower thorax | 20 | 12 | 8 | 40.0 |
Table 3 Logistic analysis on the relationship between positive rate of serum p53-Abs and clinical pathophysiological characteristics in EC patients
Variables | B | OR | 95% CI | P |
Age | 0.0241 | 1.0237 | 0.9583-1.0816 | 0.4659 |
Sex | -0.6230 | 0.5363 | 0.0863-3.3401 | 0.5165 |
TNM stage | 1.8389 | 6.2899 | 2.4658-3.8954 | 0.0248 |
Histological grade | -4.1430 | 0.0159 | 0.0039-0.5867 | 0.0156 |
Lymph node metastasis | -0.4891 | 0.5973 | 0.3327-1.1406 | 0.1314 |
Size of tumor | 0.6954 | 1.8924 | 0.7859-4.5968 | 0.1602 |
Site of tumor | -0.0695 | 0.9530 | 0.3240-2.6575 | 0.7986 |
- Citation: Cai HY, Wang XH, Tian Y, Gao LY, Zhang LJ, Zhang ZY. Changes of serum p53 antibodies and clinical significance of radiotherapy for esophageal squamous cell carcinoma. World J Gastroenterol 2008; 14(25): 4082-4086
- URL: https://www.wjgnet.com/1007-9327/full/v14/i25/4082.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.4082