Ineffective oesophageal motility: Manometric subsets exhibit different symptom profiles

Table 1 Gender, age, time since onset of symptom, and proportion of total abnormal swallows in IOM patients according to the predominant oesophageal symptom¹

	Gender (F:M)	Median age [yr (range)]	Median time since symptom onset (yr)	Total abnormal swallows (mean ± SD)(%)
Heartburn	37:16	57 (26-82)	6.7	69 ± 22
Dysphagia	28:8	63 (19-86)	2.5	68 ± 22
Chest pain	8:1	59 (31-76)	6.1	61 ± 25

¹Two male patients reported “other” predominant symptoms (hiccoughs, halitosis).

Table 2 Gender and age distribution, and ambulatory oesophageal pH data¹, for IOM manometric subsets and for patient controls who exhibited normal manometry

	Gender (F:M)	Median age [yr (range)]	AET2 (%)	Abnormal AET3 (%)	SAP+4 (%)
IOM-LAP	25:12	58 (26-77)	8.8 ± 1.8	58	52
IOM-LASC	17:7	60 (29-86)	14.7 ± 5.1	90	60
IOM-NT	31:8	61 (19-76)	11.6 ± 2.5	81	33
Patient controls	73:27	58 (19-91)	8.6 ± 0.8	69	51

¹pH data was available in 54 IOM patients and 72 patient controls;

²AET (% of time pH < 4), reported as mean ± SE;

³% of patients with an AET > 4%;

⁴Expressed as % of patients with a significant SAP value.