Treatment of abdominal compartment syndrome in severe acute pancreatitis patients with traditional Chinese medicine

doi:10.3748/wjg.14.3574

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Jun 14, 2008 (publication date) through Aug 31, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 14, 2008; 14(22): 3574-3578
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3574

Table 1 Demographic data, serum level of amylase, CTSI score, APACHE II score, ICP data and severity grade ratio of the two groups when hospitalized (mean ± SD)

	Study group (n = 40)	Control group (n = 40)
Age (yr)	54.2 ± 7.4	54.6 ± 8.1
Sex (male/female)	20/20	18/22
serum levels of amylase (U/L)	328.23 ± 13.89	354.51 ± 14.22
ICP (cmH₂O)	19.5 ± 3.4	18.7 ± 3.6
CTSI score	7.85 ± 1.1	7.90 ± 1.4
APACHE II score	17.51 ± 4.51	18.2 ± 3.87
ACS rate (%)	17.5	20.0
Severity grade (II/III)	22/8	23/7

Table 2 ICP and APACHE II score of the two groups (n = 40, mean ± SD)

	ICP			APACHE II scores
	Study group	Control group	P	Study group	Control group	P
HPd	19.5 ± 3.4	18.7 ± 3.6		17.51 ± 4.51	18.2 ± 3.87
Day 1	16.5 ± 3.2	17.4 ± 3.8		16.44 ± 3.54	17.85 ± 4.12
Day 2	15.8 ± 2.5	16.2 ± 1.9		14.21 ± 4.23	16.55 ± 3.98
Day 3	15.6 ± 2.7	15.9 ± 3.1		9.66 ± 1.88^c	13.46 ± 1.93	< 0.05
Day 4	8.2 ± 1.5^a	15.2 ± 3.7	< 0.05	7.41 ± 1.72^c	12.37 ± 2.21	< 0.05
Day 5	8.7 ± 3.2^a	14.7 ± 2.9	< 0.05	4.63 ± 1.46^c	10.78 ± 2.01	< 0.05
Day 6	7.9 ± 3.9^a	7.5 ± 3.5^a		4.33 ± 2.01^c	5.23 ± 2.67^c
Day 7	7.4 ± 2.8^a	8.1 ± 2.7^a		3.78 ± 1.53^c	4.21 ± 1.62^c

^aP < 0.05 vs ICP of HPd;

^cP < 0.05 vs APACHE II scores of HPd. HPd: Hospitalization day.

Table 3 Relief time of abdominalgia and burbulence, ascites quantity on day 7 of treatment in the two groups (mean ± SD)

	Study group (n = 40)	Control group (n = 40)	P-value
Relief time of abdominalgia (d)	4.27 ± 0.87^a	10.85 ± 1.21	0.035
Relief time of burbulence (d)	6.94 ± 1.22^a	13.27 ± 3.67	0.021
Ascites quantity (mL)	457.25 ± 34.21^a	927.84 ± 27.45	0.038

^aP < 0.05 vs control group.

Table 4 Mortality rate, cyst formation rate and hospitalization time of the two groups (mean ± SD)

	Study group (n = 40)	Control group (n = 40)	P-value
Mortality rate (%)	7.5 (3/40)	20.0 (8/40)	0.194
Cyst formation rate (%)	10.0 (4/40)^a	32.5 (13/40)	0.029
Hospitalization time (d)	16.59 ± 3.89^a	29.58 ± 4.52	0.037

^aP < 0.05 vs control group.

Citation: Zhang MJ, Zhang GL, Yuan WB, Ni J, Huang LF. Treatment of abdominal compartment syndrome in severe acute pancreatitis patients with traditional Chinese medicine. World J Gastroenterol 2008; 14(22): 3574-3578
URL: https://www.wjgnet.com/1007-9327/full/v14/i22/3574.htm
DOI: https://dx.doi.org/10.3748/wjg.14.3574