Influence of dexamethasone on mesenteric lymph node of rats with severe acute pancreatitis

Table 1 Pathological score standard of lymph node

Score	Observation indexes
1	Follicle Germinal center dilated, lymphatic sinus dilated, sinus cell hyperplasia or only lymphatic sinus dilated, sinus cell hyperplasia
2	Follicle Germinal center dilated, lymphatic sinus dilated, sinus cell hyperplasia, spotty necrosis in mantle zone and Germinal center or only lymphatic sinus dilated, and sinus cell hyperplasia, infiltration of neutrophil, eosinophile granulocyte and plasmocyte
3	Follicle Germinal center dilated, lymphatic sinus dilated, sinus cell hyperplasia, spotty necrosis in mantle zone and Germinal center, infiltration of neutrophil, eosinophile granulocyte and plasmocyte

Table 2 Comparison of different indexes level in blood (M (Q_R))

Index	Sham-operated group (h)			Model group (h)			Treated group (h)
	3	6	12	3	6	12	3	6	12
Endotoxin (EU/mL)	0.02 (0.01)	0.02 (0.01)	0.02 (0.01)	0.04 (0.02)	0.06 (0.03)	0.06 (0.02)	0.03 (0.01)	0.04 (0.01)	0.04 (0.02)
MDA (nmol/mL)	9.9 (9.9)	13.2 (6.6)	13.2 (9.9)	29.7 (6.6)	33.0 (9.9)	29.7 (14.9)	19.8 (9.9)	26.4 (13.2)	26.4 (13.2)
SOD (U/mL)	105.6 (8.3)	103.6 (6.2)	99.2 (16.2)	76.6 (13.0)	73.0 (24.5)	77.6 (12.6)	90.8 (13.4)	91.9 (11.6)	88.7 (13.7)
ET-1 (ng/L)	14.05 (1.78)	14.53 (2.082)	14.78 (2.28)	17.97 (5.57)	19.21 (7.02)	18.31 (5.06)	13.64 (1.54)	13.86 (2.64)	13.66 (2.47)

Table 3 Comparison of different pathological indexes in the lymph node (M (Q_R) )

Indexes	Sham-operated group (h)			Model group (h)			Treated group (h)
	3	6	12	3	6	12	3	6	12
Pathological score	2.0 (1.0)	2.0 (1.0)	1.0 (1.0)	2.0 (1.0)	2.0 (1.0)	2.0 (1.0)	2.0 (0.0)	2.0 (0.0)	2.0 (0.0)
P-selection	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)
Bax protein	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (1.0)	0.0 (1.0)
Bcl-2 protein	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)
Caspase-3 protein	0.0 (0.0)	0.0 (1.0)	0.0 (0.0)	0.0 (1.0)	0.0 (1.0)	0.0 (1.0)	0.0 (0.0)	0.0 (1.0)	0.0 (1.0)
Apoptotic index	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)	0.0 (0.03)	0.0 (0.0)	0.0 (0.3)	0.0 (0.4)

Table 4 Expression of Bax, Bcl-2 and P-selectin caspase-3 pathologic grade

Groups	Cases	Bax				Bcl-2			P-selectin		Caspase-3
		-	+	++	+++	-	+	++	-	+	-	+
Sham-operated group-3 h	15	12	3			15			15		12	3
Sham-operated group-6 h	15	12	0	2		15			15		11	4
Sham-operated group-12 h	15	13		1	1	15			15		12	3
Model group-3 h	15	13	2			15			14	1	11	4
Model group-6 h	15	13	1	1		15			12	3	11	4
Model group-12 h	13	13				13			12	1	9	4
Treated group-3 h	15	12	3			12	1	2	15		12	3
Treated group-6 h	15	9	4	2		15			14	1	9	6
Treated group-12 h	15	8	5	1	1	15			14	1	5	10