Small intestinal bacteria overgrowth decreases small intestinal motility in the NASH rats

Table 1 The concentration of TNF-α, liver pathologic score, serum ALT and AST levels (mean ± SD)

	n	TNF-α(ng/mL)	ALT (U/L)	AST (U/L)	Liver pathologic score
Control group	8	0.57 ± 0.09b	39.73 ± 5.10	168.00 ± 16.41	1.00 ± 0.93
NASH group	8	1.13 ± 0.15	86.63 ± 20.91d	379.63 ± 61.73d	6.00 ± 1.20d
Cidomycin group	8	0.63 ± 0.09b	70.88 ± 11.93ad	318.75 ± 52.62ad	4.25 ± 1.58ad

^bP < 0.01 vs NASH group;

^dP < 0.01 vs control group;

^aP < 0.05 vs NASH group.

Table 2 Small intestinal bacteria, small intestinal transit rate (mean ± SD)

	n	E. coli [log10(CFU/g)]	Lactobacilli [log10(CFU/g)]	Small intestinal motility(fraction)
Control group	8	1.28 ± 0.07	1.67 ± 0.16	0.58 ± 0.06
NASH group	8	1.70 ± 0.12b	1.69 ± 0.16	0.39 ± 0.11b
Cidomycin group	8	1.17 ± 0.08ad	1.81 ± 0.13	0.51 ± 0.07d

^bP < 0.01 vs control group;

^aP < 0.05 vs control group;

^dP < 0.01 vs NASH group.