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©2008The WJG Press and Baishideng.
World J Gastroenterol. Jan 14, 2008; 14(2): 211-217
Published online Jan 14, 2008. doi: 10.3748/wjg.14.211
Published online Jan 14, 2008. doi: 10.3748/wjg.14.211
Table 1 Histology/invasion depth of colorectal neoplasm in relation to type V pit pattern subtypes, n (%)
Type V pit pattern subtypes | Histology/invasion depth | |||
Dysplasia | SM < 1000&mgr;m | 1000&mgr;m ≤SM | ||
VI | 202 (100) | 117 (57.9) | 23 (11.4) | 62 (30.7) |
VN1 | 70 (100) | 0 (0) | 3 (4.3) | 67 (95.7) |
Table 2 Histology/invasion depth of colorectal neoplasm with type VI pit pattern in relation to detailed magnifying colonoscopy findings, n (%)
Magnifying | Histology/invasion depth | |||
colonoscopy | ||||
finding | Dysplasia | SM < 1000&mgr;m | 1000&mgr;m ≤SM | |
Irregular pit | 79 (100) | 23 (29.1) | 10 (12.7) | 46 (58.2) |
margins1 | ||||
Unclear staining | 87 (100) | 21 (24.1) | 16 (18.4) | 50 (57.5) |
characteristics | ||||
of the area | ||||
between pits1 | ||||
Area diameter | 138 (100) | 65 (47.1) | 16 (11.6) | 57 (41.3) |
of type VI pit | ||||
pattern ≥ 5 mm1 | ||||
High residual | 109 (100) | 64 (58.7) | 16 (14.7) | 29 (26.6) |
pit density | ||||
Wide intervening | 138 (100) | 81 (58.7) | 13 (9.4) | 44 (31.9) |
membrane | ||||
between pits |
Table 3 Results of multivariate logistic regression analysis for predictors of submucosal invasion deeper than 1000 &mgr;m (n = 202)
Magnifying colonoscopy finding | Odds ratio (P value) | Relevant finding |
Unclear staining characteristics of the areas between pits | 6.24 (< 0.0001) | Clear staining characteristics of the areas between pits |
Irregular pit margins | 4.89 (< 0.0001) | Regular pit margins |
Area diameter of type VI pit pattern ≥ 5 mm | 4.14 (0.0132) | Area diameter of type VI pit pattern < 5 mm |
High residual pit density | 1.51 (0.3335) | Low residual pit density |
Wide intervening membrane between pits | 1.02 (0.9740) | Narrow intervening membrane between pits |
Table 4 Histology/invasion depth of colorectal neoplasm in relation to type VI pit pattern subclassifications, n (%)
Type VI pit pattern subclassification | Histology/invasion depth | |||
Dysplasia | SM < 1000&mgr;m | 1000&mgr;m ≤SM | ||
Mildly irregular1 | 104 (100) | 89 (85.6) | 8 (7.7) | 7 (6.7) |
Severely irregular | 98 (100) | 28 (28.6) | 15 (15.3) | 55 (56.1) |
Table 5 Status of muscularis mucosae in relation to type V pit patterns, n (%)
Table 6 Desmoplastic reaction at the lesion surface in relation to type V pit pattern, n (%)
Desmoplastic reaction | ||||
Type V pit pattern | Absent (-) | Mild to moderate (+) | Severe (++) | |
VI | ||||
Mildly irregular | 104 (100) | 100 (96.2) | 4 (3.8) | |
Severely irregular | 98 (100) | 48 (49.0) | 29 (29.6) | 21 (21.4) |
VNb | 67 (100) | 16 (23.9) | 51 (76.1) |
- Citation: Kanao H, Tanaka S, Oka S, Kaneko I, Yoshida S, Arihiro K, Yoshihara M, Chayama K. Clinical significance of type VI pit pattern subclassification in determining the depth of invasion of colorectal neoplasms. World J Gastroenterol 2008; 14(2): 211-217
- URL: https://www.wjgnet.com/1007-9327/full/v14/i2/211.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.211