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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Apr 14, 2008; 14(14): 2255-2261
Published online Apr 14, 2008. doi: 10.3748/wjg.14.2255
Published online Apr 14, 2008. doi: 10.3748/wjg.14.2255
Table 1 Relationship between variables and alcohol-related liver injury detected by using univariate logistic-regression
Variable | β | S.E. | Waldχ2 | P | OR | 95% CI |
Male gender | 1.152 | 0.228 | 25.448 | 0.000 | 3.163 | 2.022-4.948 |
Age | -0.008 | 0.007 | 1.162 | 0.281 | 0.992 | 0.978-1.006 |
Education level | 0.061 | 0.127 | 0.229 | 0.632 | 1.063 | 0.829-1.362 |
Unmarried state | -0.144 | 0.408 | 0.125 | 0.724 | 0.866 | 0.389-1.926 |
Smoking | 0.810 | 0.190 | 18.184 | 0.000 | 2.248 | 1.549-3.262 |
Daily alcohol intake ≥ 20 g | 1.460 | 0.201 | 52.562 | 0.000 | 4.307 | 2.902-6.392 |
Duration of drinking ≥ 5 years | 1.729 | 0.237 | 53.324 | 0.000 | 5.633 | 3.542-8.958 |
Total alcohol intake ≥ 36.5 kg | 1.506 | 0.208 | 52.582 | 0.000 | 4.507 | 3.000-6.711 |
Hypertension | 0.473 | 0.209 | 5.128 | 0.024 | 1.605 | 1.066-2.418 |
Obesity | 0.671 | 0.188 | 12.673 | 0.000 | 1.956 | 1.352-2.829 |
Table 2 Multivariate logistic-regression analysis of alcohol-related liver injury and selected variables
Variable | β | S.E. | Waldχ2 | P | OR | 95% CI |
Daily alcohol intake ≥ 20 g | 0.676 | 0.286 | 5.584 | 0.018 | 1.965 | 1.122-3.442 |
Duration of drinking ≥ 5 years | 1.227 | 0.329 | 13.884 | 0.000 | 3.412 | 1.789-6.507 |
Obesity | 0.635 | 0.206 | 9.518 | 0.002 | 1.887 | 1.261-2.824 |
Table 3 Prevalence rate of alcohol-related liver injury (%)
Variable | Total ALI | ALI in obese | ALI in non-obese | |||
Daily alcohol intake(g) | ||||||
< 20 | 45/373 | (12.06) | 22/157 | (14.01) | 23/216 | (10.65) |
≥ 20 | 104/280 | (37.14) | 60/119 | (50.42) | 44/161 | (27.33) |
Duration of drinking (yr) | ||||||
<5 | 25/293 | (8.53) | 12/118 | (10.17) | 13/175 | (7.43) |
≥ 5 | 124/360 | (34.44) | 70/158 | (44.30) | 54/202 | (26.73) |
Table 4 Relationship between different daily alcohol intake and BMI
Group | ALI | Normal | χ2 | P | OR | 95%CI |
X0 | 23 | 193 | - | - | - | - |
X1 | 44 | 117 | 17.564 | 0.000 | 3.156 | 1.813-5.492 |
X2 | 22 | 135 | 0.970 | 0.325 | 1.367 | 0.732-2.553 |
X3 | 60 | 59 | 65.121 | 0.000 | 8.534 | 4.864-14.972 |
Y0 | 13 | 162 | - | - | - | - |
Y1 | 54 | 148 | 23.911 | 0.000 | 4.547 | 2.385-8.668 |
Y2 | 12 | 106 | 0.678 | 0.410 | 1.411 | 0.620-3.209 |
Y3 | 70 | 88 | 60.338 | 0.000 | 9.913 | 5.194-18.918 |
Table 5 Dose-response to daily alcohol intake, drinking time and alcohol-related liver injury
Characteristics | Total | ALI | χ2 | P | OR (95%CI) | PR (%) | PR |
Daily alcohol intake (g) | |||||||
< 20 | 373 | 45 | - | - | - | 12.06 | 1.00 |
20-40 | 76 | 25 | 20.817 | 0.000 | 3.573 (2.019-6.324) | 32.89 | 2.73 |
40-80 | 73 | 27 | 28.011 | 0.000 | 4.278 (2.424-7.552) | 36.99 | 3.07 |
80-160 | 65 | 24 | 25.774 | 0.000 | 4.267 (2.360-7.715) | 36.92 | 3.06 |
≥ 160 | 66 | 28 | 37.283 | 0.000 | 5.371 (3.010-9.584) | 42.42 | 3.52 |
Duration of drinking (yr) | |||||||
< 5 | 293 | 25 | - | - | - | 8.53 | 1.00 |
5-10 | 22 | 4 | 2.279 | 0.131 | 2.382 (0.748-7.587) | 18.18 | 2.13 |
10-20 | 58 | 22 | 36.082 | 0.000 | 6.551 (3.351-12.806) | 37.93 | 4.45 |
20-40 | 206 | 76 | 60.265 | 0.000 | 6.267 (3.808-10.313) | 36.89 | 4.32 |
≥ 40 | 74 | 22 | 23.773 | 0.000 | 4.535 (2.379-8.647) | 29.73 | 3.49 |
Table 6 Different types of alcoholic beverage and alcohol-related liver injury
Type of beverage | Total | ALI (n, %) | Daily intake (g) | χ2 | P |
Beer | 126 | 38 (30.16) | 40.26 ± 31.35 | - | - |
Yellow rice wine | 36 | 14 (38.89) | 78.15 ± 57.88 | 0.979 | 0.322 |
Hard liquor | 41 | 16 (39.02) | 107.09 ± 84.38 | 1.111 | 0.292 |
Multiple | 110 | 44 (40.00) | 167.26 ± 109.60 | 2.509 | 0.113 |
Total | 313 | 112 (35.78) |
- Citation: Shen Z, Li YM, Yu CH, Shen Y, Xu L, Xu CF, Chen JJ, Ye H, Xu GY. Risk factors for alcohol-related liver injury in the island population of China: A population-based case-control study. World J Gastroenterol 2008; 14(14): 2255-2261
- URL: https://www.wjgnet.com/1007-9327/full/v14/i14/2255.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.2255