Dynamic changes of IL-2/IL-10, sFas and expression of Fas in intestinal mucosa in rats with acute necrotizing pancreatitis

Table 1 IL-2 and IL-10 level in each group (mean ± SD, n = 8) (pg/mL)

Group		0.5 h	2 h	6 h	12 h
IL-2	C	2.79 ± 0.51	2.93 ± 0.89	4.81 ± 1.23	3.41 ± 0.72
	P	3.53 ± 0.62b	4.35 ± 1.11b	6.94 ± 1.55b	4.80 ± 1.10b
IL-10	C	54.61 ± 15.81	141.15 ± 40.21	89.18 ± 32.52	77.15 ± 22.60
	P	47.34 ± 14.62	156.12 ± 43.10	494.98 ± 11.23b	93.28 ± 25.81b

^bP < 0.01 vs control group.

Table 2 Serum IL-2/IL-10 AND Serum sFas in each group (mean ± SD, n = 8)

Group		0.5 h	2 h	6 h	12 h
IL-2/IL-10	C	0.05 ± 0.01	0.02 ± 0.01	0.05 ± 0.02	0.04 ± 0.01
	P	0.07 ± 0.02b	0.03 ± 0.01b	0.01 ± 0.01b	0.05 ± 0.02
sFas (pg/mL)	C	3.16 ± 0.75	4.05 ± 1.08	5.93 ± 1.52	4.62 ± 1.23
	P	3.31 ± 0.80a	4.32 ± 1.11a	5.41 ± 1.47a	4.44 ± 1.16a

^aP > 0.05 vs control group,

^bP < 0.01 vs control group.

Table 3 Intestinal mucosal injury in each group (n = 8)

Group	0.5 h						2 h						6 h						12 h
	0	1	2	3	4	5	0	1	2	3	4	5	0	1	2	3	4	5	0	1	2	3	4	5
C	7	1	0	0	0	0	6	2	0	0	0	0	7	1	0	0	0	0	6	2	0	0	0	0
P	0	2	5	1	0	0b	0	0	2	4	2	0b	0	0	0	1	4	3b	0	0	0	0	3	5b

^bP < 0.01 vs C group.