Clinical value of fecal calprotectin in determining disease activity of ulcerative colitis

Table 1 Concentrations of fecal calprotectin, CRP, ESR and AGP in the UC patients and the controls (mean ± SD)

Group	Calprotectin (&mgr;g/g)	CRP (mg/L)	ESR (mm/H)	AGP (mg/L)
Control	11.5 ± 3.42	2.66 ± 3.2	7.05 ± 1.2	786.65 ± 77.65
Inactive UC	35.93 ± 3.39	4.39 ± 0.89	9.84 ± 1.36	870.14 ± 71.04
Active UC	402.16 ± 48.0	16.45 ± 3.98	21.44 ± 3.29	1394.9 ± 109.3

UC: Ulcerative colitis; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; AGP: Acid glycoprotein.

Table 2 Specificity and sensitivity for fecal calprotectin, CRP, ESR and AGP

Marker	Cut-off	Specificity (%)	Sensitivity (%)
Fecal calprotectin	50.0 &mgr;g/g	79.4	91.9
CRP	5.0 mg/L	69.0	62.2
ESR	15.0 mm/h	68.9	64.9
AGP	1200 mg/L	65.5	67.6