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©2007 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 14, 2007; 13(46): 6208-6212
Published online Dec 14, 2007. doi: 10.3748/wjg.v13.i46.6208
Published online Dec 14, 2007. doi: 10.3748/wjg.v13.i46.6208
Table 1 Diagnosis and/or etiology of pancreatitis in the control and study groups
Control group | n (%) | Study group | n (%) |
Familial Mediterranean fever | 5 (20) | Gallstone | 58 (63.0) |
Acute appendicitis | 5 (20) | Idiopatic | 18 (19.6) |
Acute cholecystitis | 4 (16) | Post-ERCP | 8 (8.7) |
Perforated peptic ulcer | 3 (12) | Alcohol | 5 (5.4) |
Acute cholangitis | 2 (8) | Hypertriglyceridemia | 3 (3.3) |
Pelvic inflammatory disease | 2 (8) | ||
Intestinal obstruction | 2 (8) | ||
Gastric cancer | 1 (4) | ||
Meckel diverticulitis | 1 (4) |
Table 2 Demographics and results for control and study groups
Control group(n = 25) | Study group(n = 92) | P | |
Age (yr)1 | 59.2 ± 13.5 (34-78) | 58.9 ± 14.2 (36-80) | 0.928 |
Gender (F/M) | 15/10 | 69/23 | 0.113 |
BMI (kg/m2)1 | 23.5 ± 3.4 (16-30) | 24.0 ± 3.8 (16-33) | 0.902 |
Amylase (> 100 U/L)1 | 67 ± 32.5 (18-176) | 600.8 ± 189.7 (376-1250) | 0.000 |
Lipase (> 60 U/L)1 | 33.8 ± 15 (13-65) | 96.2 ± 42.4 (58-230) | 0.000 |
UTDT +/- (on admission) | 2/23 | 87/5 | 0.000 |
UTDT +/- (48 h later) | 1/23 | 87/5 | 0.000 |
Duration of UTDT positivity (d)1 | 2.0 ± 1.4 (1-3) | 3.6 ± 2.1 (2-13) | 0.000 |
APACHE II score (on admission)1 | 4.6 ± 1.5 (3-8) | 6.1 ± 2.7 (3-13) | 0.006 |
Table 3 Demographics and results for control and study groups (Classified as mild and severe AP)
Control | Mild AP | Severe AP | P1 | P2 | P3 | |
(n = 25) | (n = 66) | (n = 26) | ||||
Age (yr)4 | 59.2 ± 13.5 | 58.7 ± 14.3 | 60.2 ± 14.9 | 0.883 | 0.796 | 0.655 |
Gender (F/M) | 15/10 | 51/15 | 17/9 | 0.118 | 0.776 | 0.365 |
BMI (kg/m2)4 | 23.5 ± 3.4 | 23.5 ± 3.9 | 24.2 ± 4.1 | 0.627 | 0.507 | 0.217 |
Amylase (> 100 U/L)4 | 67 ± 32.5 | 578.6 ± 171 | 658.2 ± 222 | 0.000 | 0.000 | 0.068 |
Lipase (> 60 U/L)4 | 33.8 ± 1 | 76.0 ± 23.9 | 110.4 ± 54.2 | 0.000 | 0.000 | 0.000 |
Positive UTDT | 2/23 | 61/5 | 26/0 | 0.000 | 0.000 | 0.351 |
(on admission) | ||||||
Positive UTDT | 1/24 | 61/5 | 26/0 | 0.000 | 0.003 | 0.351 |
(48 h later) | ||||||
Duration of UTDT positivity (d)4 | 2.0 ± 1.4 | 2.6 ± 0.6 | 6.2 ± 2.5 | 0.000 | 0.000 | 0.000 |
APACHE-II score | 4.6 ± 1.5 | 4.7 ± 1.4 | 9.7 ± 1.8 | 0.807 | 0.000 | 0.000 |
(on admission)4 | ||||||
APACHE-II score | - | 4.24 ± 1.4 | 11.5 ± 2.9 | - | - | 0.000 |
(after 48 h)4 | ||||||
Ranson score | - | 1.03 ± 0.8 | 3.73 ± 1 | - | - | 0.000 |
(on admission) > 24 |
Table 4 Sensitivity, specificity, PPV, NPV, PLR and NLR of serum amylase, serum lipase, UTDT and APACHE II scoring systems in AP
Sensitivity | Specificity | PPV | NPV | PLR | NLR | |
% | % | % | % | |||
On admission | ||||||
Serum amylase (> 100 U/L) | 78.0 | 87.3 | 94.8 | 61.5 | 6.1 | 0.3 |
Serum lipase (> 60 U/L) | 86.2 | 89.4 | 96.6 | 76.0 | 8.1 | 0.2 |
UTDT, positive | 91.0 | 72.0 | 96.6 | 70.4 | 3.4 | 0.1 |
APACHE II > 8 | 56.0 | 89.4 | 61.0 | 84.2 | 5.3 | 0.5 |
Table 5 Comparisons of sensitivity and specificity of UTDT in AP in present study with those reported previously
- Citation: Kamer E, Unalp HR, Derici H, Tansug T, Onal MA. Early diagnosis and prediction of severity in acute pancreatitis using the urine trypsinogen-2 dipstick test: A prospective study. World J Gastroenterol 2007; 13(46): 6208-6212
- URL: https://www.wjgnet.com/1007-9327/full/v13/i46/6208.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i46.6208