Influence of dexamethasone on inflammatory mediators and NF-κB expression in multiple organs of rats with severe acute pancreatitis

Table 1 Comparison of plasma amylase [M (Q_R)]

Group (time/h)	3 h	6 h	12 h
Sham operation	2038.00 (346.00)	2117.00 (324.00)	1725.00 (434.00)
Model	7423.00 (2275.00)	8149.00 (1540.00)	9195.00 (1298.00)
Treatment	6739.00 (2310.00)	7839.00 (2258.00)	7791.00 (1863.00)

Table 2 Comparison of plasma endotoxin [M (Q_R)]

Group (time/h)	3 h	6 h	12 h
Sham operation	0.015 (0.007)	0.015 (0.007)	0.016 (0.005)
Model	0.035 (0.0170)	0.055 (0.025)	0.059 (0.020)
Treatment	0.030 (0.0140)	0.040 (0.012)	0.042 (0.018)

Table 3 Comparison of serum TNF-α [M (Q_R)]

Group (time/h)	3 h	6 h	12 h
Sham operation	3.30 (3.60)	4.90 (2.60)	3.70 (2.30)
Model	46.13 (37.95)	77.54 (42.16)	67.30 (32.13)
Treatment	38.40 (26.60)	58.30 (26.40)	38.70 (28.50)

Table 4 The changes of expression level of NF-κB in the liver

Group	(Time/h)	Cases	Pathologic grade
			-	+	++	+++
Sham operation	3	15	15	0	0	0
	6	15	15	0	0	0
	12	15	15	0	0	0
Model	3	15	7	4	4	0
	6	15	10	3	2	0
	12	13	11	1	1	0
Treatment	3	15	12	1	2	0
	6	15	11	1	3	0
	12	15	9	3	3	0

Table 5 Comparison of the expression level of NF-κB in the liver [M (Q_R)]

Group	3 h	6 h	12 h
Sham operation	0.00 (0.00)	0.00 (0.00)	0.00 (0.00)
Model	1.00 (2.00)	0.00 (1.00)	0.00 (0.00)
Treatment	0.00 (0.00)	0.00 (1.00)	0.00 (1.00)

Table 6 The changes of expression level of NF-κB in the kidney

Group	(Time/h)	Cases	Pathologic grade
			-	+	++	+++
Sham operation	3	15	15	0	0	0
	6	15	15	0	0	0
	12	15	15	0	0	0
Model	3	15	13	1	1	0
	6	15	12	1	2	0
	12	13	13	0	0	0
Treatment	3	15	12	2	1	0
	6	15	13	0	2	0
	12	15	9	2	3	1

Table 7 Comparison of the expression level of NF-κB in the kidney [M (Q_R)]

Group	3 h	6 h	12 h
Sham operation	0.00 (0.00)	0.00 (0.00)	0.00 (0.00)
Model	0.00 (0.00)	0.00 (0.00)	0.00 (0.00)
Treatment	0.00 (0.00)	0.00 (0.00)	0.00 (2.00)