Leptin levels in the differential diagnosis between benign and malignant ascites

Table 1 Demographic and anthropometrical characteristics of all subjects

Characteristic	Mean age ± SD(yr)	BMI(kg/m2)	BFP(%)	BFM(kg)
Cirrhotic patients (n = 30)	55.05 ± 13.26	22.1	26.4	17.3
Male (n = 15)	57.2 ± 12.3	21.5	23.8	16.6
Female (n = 15)	53.3 ± 13.05	22.6	28.8	17.9
Malignant ascites (n = 35)	56.2 ± 17.4	22.4	26.8	17.4
Male (n = 20)	58.2 ± 15.3	22.1	24.2	17.1
Female (n = 15)	54.1 ± 14.2	22.8	29.4	17.9
Tuberculous peritonitis (n = 12)	51.9 ± 15.3	22.6	26.9	17.6
Male (n = 5)	53.8 ± 13.2	22.2	24.6	17.2
Female (n = 7)	50.1 ± 12.4	23	29.4	18.1
Control (n = 20)	52.9 ± 13.3	22.7	27	17.7
Male (n = 10)	54.6 ± 11.8	22.5	24.8	17.3
Female (n = 10)	51.6 ± 10.9	22.9	29.2	18.2

Table 2 Ascitic leptin, TNFα and serum leptin levels in study population (mean ± SD)

	Controlsubjects	Cirrhoticpatients	Malignantascites	Tuberculousperitonitis
Leptin (ascites) (μg/L)	-	7.19 ± 3.43	2.45 ± 1.25	5.59 ± 1.08
Leptin (serum) (μg/L)	2.93 ± 0.32	3.77 ± 2.04	1.30 ± 0.63	3.72 ± 0.64
TNFα (ascites) (ng/L)	-	30.36 ± 6.37	29.65 ± 7.08	65.5 ± 18.4
Total proteins (ascites) (g/L)	-	15.4 ± 6.3	26.1 ± 11.5	28.2 ± 21.9
Albumin (ascites) (g/L)	-	7.1 ± 4.0	14.3 ± 7.2	13 ± 11.6
LDH (ascites) (U/L)	-	142.97 ± 93.99	546.5 ± 473.8	351.40 ± 378.82
Glucose (ascites) (mg/L)	-	1253.6 ± 348.1	1057.2 ± 443.8	1176 ± 482.3
Total leukocyte (ascites) ( × 106/L)	-	0.43 ± 0.46	976 ± 608.4	1.16 ± 1.17
Neutrophils (ascites) ( × 106/L)	-	0.22 ± 0.31	668.19 ± 416.3	0.44 ± 0.63
Lymphocytes (ascites) ( × 106/L)	-	0.12 ± 0.01	223.34 ± 102.3	0.75 ± 0.32