Clinicopathologic significance of BAG1 and TIMP3 expression in colon carcinoma

Table 1 Expression of BAG1 and TIMP3

Tissue type	n	BAG1	TIMP3
		Positive number (%)	Positive number (%)
Benign	20	2 (10.00)	12 (60.00)
Malignant	80	64 (80.00)a	35 (43.75)

^aP < 0.05 vs benign group.

Table 2 Clinicopathologic index

Clinico-pathologicindex		n	BAG1		TIMP3
			Positivenumber	χ2 value	Positivenumber	χ2 value
Age	≥ 50	59	50	2.13	29	2.67
	< 50	21	14		6
Sex	Male	47	38	0.05	17	0.007
	Female	33	26		18
Stage	Duke’s A	24	10	11.35	16	7.9
	Duke’s B	22	18a		9a
	Duke’s C	21	20a		7a
	Duke’s D	13	12a		3a
Differen	Well	28	17	9.92	19	10.97
-tiation	Moderate	37	33a		13a
	Poorly	15	14a		3a
Lymphonode	Yes	32	30	6.3	5	17.14
metastasis	No	48	34a		30a
Survival	≥ 5 yr	38	26	6.07	27	21.92
	< 5 yr	42	38a		8a

^aP < 0.05.

Table 3 Correlation between BAG1 and TIMP3 expression

Detection index	BAG1	χ2 value	P value r value
	Positive Negative
TIMP3 Positive	25 10	2.86	P > 0.05 0.0856
Negative	39 6