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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 28, 2007; 13(28): 3847-3854
Published online Jul 28, 2007. doi: 10.3748/wjg.v13.i28.3847
Published online Jul 28, 2007. doi: 10.3748/wjg.v13.i28.3847
Table 1 A global view of differential gene expression
Categories | Number of up-regulatedgenes | Number of down-regulatedgenes | ||
4 h | 18 h | 4 h | 18 h | |
|SLR| < 1 | 1527 | 1225 | 131 | 73 |
|SLR| ≥ 1 | 276 | 395 | 447 | 70 |
|SLR| ≥ 2 | 64 | 188 | 92 | 17 |
|SLR| ≥ 3 | 21 | 95 | 60 | 10 |
|SLR| ≥ 4 | 4 | 32 | 27 | 7 |
Total | 1803 | 1620 | 578 | 143 |
Table 2 Levels of sIL-2R, ALT, and HBV DNA in the sera of patients with chronic HBV infection (mean ± SD)
Probe set | Gene symbol | 4 h (SLR) | 18 h(SLR) | Gene title |
1423754_at | 1110004C05Rik | 0.9 | 0.8 | RIKEN cDNA 1110004C05 gene |
1425156_at | 9830147J24Rik | 0.4 | 1.6 | RIKEN cDNA 9830147J24 gene |
1452428_a_at | B2m | 0.5 | 0.4 | beta-2 microglobulin |
1418021_at | C4 | 0.3 | 0.3 | Complement component 4 (within H-2S) |
1418126_at | Ccl5 | 0.3 | 0.3 | Chemokine (C-C motif) ligand 5 |
1419609_at | Ccr1 | 1.1 | 0.4 | Chemokine (C-C motif) receptor 1 |
1418930_at | Cxcl10 | 0.3 | 1.2 | Chemokine (C-X-C motif) ligand 10 |
1417876_at | Fcgr1 | 1.5 | 0.4 | Fc receptor, IgG, high affinity I |
1431591_s_at | G1p2 | 1.7 | 1.6 | interferon, alpha-inducible protein |
1420549_at | Gbp1 | 0.6 | 0.7 | Guanylate nucleotide binding protein 1 |
1435906_x_at | Gbp2 | 0.7 | 0.2 | Guanylate nucleotide binding protein 2 |
1421596_s_at | H28 | 1.9 | 1.4 | Histocompatibility 28 |
1425917_at | H28 | 1.5 | 1.8 | Histocompatibility 28 |
1451721_a_at | H2-Ab1 | 0.3 | 0.2 | Histocompatibility 2, class II antigen A, beta 1 |
1426324_at | H2-D1 | 0.7 | 0.7 | Histocompatibility 2, D region locus 1 |
1424948_x_at | H2-K | 0.3 | 0.6 | Histocompatibility 2, K region |
1425336_x_at | H2-K | 0.3 | 0.3 | Histocompatibility 2, K region |
1452544_x_at | H2-K | 0.5 | 0.3 | Histocompatibility 2, K region |
1421358_at | H2-M3 | 0.5 | 0.2 | Histocompatibility 2, M region locus 3 |
1449875_s_at | H2-T10 | 0.6 | 0.4 | histocompatibility 2, T region locus 10 |
1449556_at | H2-T23 | 0.3 | 0.2 | Histocompatibility 2, T region locus 23 |
1419603_at | Ifi16 | 4.6 | 4.2 | Interferon, gamma-inducible protein 16 |
1421551_s_at | Ifi202b | 1.5 | 0.9 | Interferon activated gene 202B |
1452348_s_at | Ifi205 | 0.5 | 0.4 | Interferon activated gene 205 |
1452349_x_at | Ifi205 | 0.8 | 0.7 | Interferon activated gene 205 |
1450783_at | Ifit1 | 0.8 | 0.6 | Interferon-induced protein with tetratricopeptide repeats 1 |
1449025_at | Ifit3 | 1.1 | 0.8 | Interferon-induced protein with tetratricopeptide repeats 3 |
1418219_at | Il15 | 1.6 | 1.4 | Interleukin 15 |
1416296_at | Il2rg | 0.5 | 0.6 | Iinterleukin 2 receptor, gamma chain |
1449399_a_at | Il1b | 0.9 | 0.4 | Interleukin 1 beta |
1421322_a_at | Isgf3g | 0.3 | 0.4 | Iinterferon-dependent positive acting transcription factor 3 gamma |
1425436_x_at | Klra3 | 0.7 | 0.1 | Killer cell lectin-like receptor, subfamily A, member 3 |
1417185_at | Ly6a | 0.9 | 0.9 | Lymphocyte antigen 6 complex, locus A |
1421571_a_at | Ly6c | 0.7 | 0.3 | Lymphocyte antigen 6 complex, locus C |
1416930_at | Ly6d | 0.6 | 0.5 | Lymphocyte antigen 6 complex, locus D |
1422089_at | Ncr1 | 1.4 | 1.0 | Natural cytotoxicity triggering receptor 1 |
1453196_a_at | Oasl2 | 2.1 | 1.9 | 2'-5' oligoadenylate synthetase-like 2 |
1422962_a_at | Psmb8 | 0.4 | 0.3 | Proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional protease 7) |
1450696_at | Psmb9 | 0.8 | 0.6 | Proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional protease 2) |
1417056_at | Psme1 | 0.5 | 0.4 | Proteasome (prosome, macropain) 28 subunit, alpha |
1418131_at | Samhd1 | 0.6 | 0.2 | SAM domain and HD domain, 1 |
1421812_at | Tapbp | 0.3 | 0.5 | TAP binding protein |
1425324_x_at | Igh-4 | -1.7 | -2.1 | Immunoglobulin heavy chain 4 (serum IgG1) |
1429381_x_at | Igh-VJ558 | -1.2 | -1.4 | Immunoglobulin heavy chain (J558 family) |
1451632_a_at | Igh-1 | -2 | -2.5 | Immunoglobulin heavy chain 1 (serum IgG2a) |
- Citation: Liu JW, Cheng J. Molecular mechanism of immune response induced by foreign plasmid DNA after oral administration in mice. World J Gastroenterol 2007; 13(28): 3847-3854
- URL: https://www.wjgnet.com/1007-9327/full/v13/i28/3847.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i28.3847