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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 14, 2007; 13(22): 3084-3089
Published online Jun 14, 2007. doi: 10.3748/wjg.v13.i22.3084
Published online Jun 14, 2007. doi: 10.3748/wjg.v13.i22.3084
Symptoms | GeneVac-B (48) | Engerix B (38) | Shanvac B (32) |
Mild fever | 4 (8.3) | 3 (7.8) | 3 (9.3) |
Moderate fever | 3 (6.2) | 2 (5.2) | 2 (6.2) |
Excessive crying | 1 (2) | 1 (2.6) | 1 (3.1) |
Irritability | 2 (4.1) | 1 (2.6) | 1 (3.1) |
Local swelling | 2 (4.1) | 3 (6.8) | 2 (6.2) |
Local erythema | 2 (4.1) | 2 (5.2) | 2 (6.2) |
Induration | 1 (2) | 1 (2.6) | 1 (3.1) |
Rash | 1 (2) | nil | 1 (3.1) |
Parameters | 1st dose | 2nd dose | 3rd dose | After one year |
Group-I- GeneVac-B | ||||
No. of infants | 58 | 48 | 48 | 35 |
Seroconversion | 57.10% | 94.20% | 100% | 100% |
Seroprotection | 22.80% | 82.80% | 100% | 100% |
GMT (mIu/mL) | 11.6 | 35.4 | 93.5 | 226.7 |
Group-II- Engerix B | ||||
No. of infants | 50 | 43 | 38 | 21 |
Seroconversion | 57.10% | 90.00% | 100% | 100% |
Seroprotection | 19.00% | 71.40% | 100% | 100% |
GMT (mIu/mL) | 8.4 | 24.4 | 80.9 | 197.9 |
Group-III Shanvac B | ||||
No. of infants | 50 | 45 | 32 | 12 |
Seroconversion | 50% | 91.60% | 100% | 100% |
Seroprotection | 16.60% | 66.60% | 100% | 100% |
GMT (mIu/mL) | 8 | 18.6 | 72.55 | 173.6 |
- Citation: Velu V, Nandakumar S, Shanmugam S, Jadhav SS, Kulkarni PS, Thyagarajan SP. Comparison of three different recombinant hepatitis B vaccines: GeneVac-B, Engerix B and Shanvac B in high risk infants born to HBsAg positive mothers in India. World J Gastroenterol 2007; 13(22): 3084-3089
- URL: https://www.wjgnet.com/1007-9327/full/v13/i22/3084.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i22.3084