Ginkgo biloba extract (EGb 761) attenuates lung injury induced by intestinal ischemia/reperfusion in rats: Roles of oxidative stress and nitric oxide

Table 1 Changes in W/D and PPI in lung tissues (mean ± SD)

	n	Sham	II/R	EGb +II/R
PPI (× 10-3)	8	1.08 ± 0.42	4.02 ± 0.82b	2.23 ± 0.45ac
W/D (%)	8	13.75 ± 5.18	29.62 ± 3.39a	16.34 ± 6.45d

^aP < 0.05,

^bP < 0.01 vs sham group;

^cP < 0.05,

^dP < 0.01 vs II/R group. W/D: Wet-to-dry lung weight ratio, PPI: pulmonary permeability index.

Table 2 Changes in the activities of SOD and MPO, the levels of MDA and NO₂^-/NO₃^- in lung tissues (mean ± SD)

	n	Sham	II/R	EGb + II/R
MDA (nmol/100 mg)	8	41.34 ± 6.45	68.52 ± 8.69b	44.56 ± 6.13d
SOD activity (U/100 mg)	8	101.8 ± 10.32	61.09 ± 6.52b	84.36 ± 8.25ac
NO2-/NO3- (μmol/100 mg)	8	40.36 ± 9.68	78.54 ± 12.36b	44.13 ± 8.56d
MPO activity (U/g)	8	3.26 ± 0.78	6.93 ± 0.79b	4.14 ± 0.76ad

^aP < 0.05,

^bP < 0.01 vs sham group;

^cP < 0.05,

^dP <0.01 vs II/R group. MPO: Myeloperoxidase; NO₂^-/NO₃^-: nitrite/nitrate; MDA: malondialdehyde; SOD: superoxide dismutase.