Impact of endoscopic ultrasound-guided fine needle biopsy for diagnosis of pancreatic masses

Table 1 Distribution of patients according to the final diagnosis and number of patients correctly diagnosed by cytological and histological evaluation of samples obtained by EUS-guided FNA

Final diagnosis	n	Correctdiagnosisby cytology	Correctdiagnosisby histology	Correct diagnosisby both cytologyand histology
Adenocarcinoma	33	24	21	27
Anaplastic carcinoma	1	1	1	1
Small cell lung cancer	1	0	1	1
Squamous cell carcinoma	1	1	1	1
B cell lymphoma	1	0	1	1
Endocrine carcinoma	1	0	1	1
Inflammatory process	24	17	24	24
Total	62	42	55	56

Table 2 Accuracy of EUS-guided FNA for detection of malignancy in pancreatic solid masses in cases of adequate FNA sampling (95% CI)

	Cytology	Histology	P
Sensitivity	76.5% (60.0-87.6)	92.85% (77.3-98.0)	0.097
Specificity	100% (81.6-100)	100% (86.2-100)	NS
Negative predictive value	68.0% (48.4-82.8)	92.3% (75.9-97.9)a	< 0.05
Positive predictive value	100% (87.1-100)	100% (87.1-100)	NS
Overall accuracy	84.3% (72.0-91.8)	96.1% (87.0-98.9)	0.05

NS: not significant.

^aP < 0.05 vs cytology.