Twenty-four hour intra-arterial infusion of 5-fluorouracil, cisplatin, and leucovorin is more effective than 6-hour infusion for advanced hepatocellular carcinoma

Table 1 Clinical characteristic of the 37 patients with advanced HCC and HCV cirrhosis

Mean age	Group S: 68.3 yr
	Group L: 66.6 yr
Gender	Group S: 10 males, 15 females
	Group L: 15 males, 7 females
Child-Pugh classification	Group S A: 6, B: 7, C: 2
	Group L A: 11, B: 9, C: 2
Stage	Group S III: 2, IVA: 12, IVB: 1
	(Vp3: 4, Vp4: 1, vv2: 0)
	Group L III: 1, IVA: 14, IVB: 7
	(Vp3: 3, Vp4: 0, vv2: 1)
JIS score	Group S 3: 7, 4: 7, 5: 1
	Group L 3: 12, 4: 8, 5: 2

Table 2 Objective response and survival in the both group (%)

	Group	JIS score
		3	4	5
1-yr	Group S	14.3	0.0	0.0
	Group L	50.0	16.7	16.7
2-yr	Group S	0.0	0.0	0.0
	Group L	16.7	0.0	0.0
3-yr	Group S	0.0	0.0	0.0
	Group L	16.7	0.0	0.0

Objective response rate: Group S 6.7% (1/15 cases) CR: PR: SD: PD = 0: 1: 3: 11; Group L 31.8% (7/22 cases) CR: PR: SD: PD = 0: 7: 9: 6.