Proximal gastric motility in critically ill patients with type 2 diabetes mellitus

Table 1 Demographic characteristics of the critically ill patients and healthy subjects

	Diabetic ICUpatients(n = 10)	Non-diabeticICU patients(n = 15)	Healthysubjects(n = 10)
Age (yr)	59 ± 3a	48 ± 5a	28 ± 3
Gender (M:F)	5:5	12:3	7:3
BMI (kg/m2)	35 ± 3c	27 ± 1	25 ± 1
APACHE II score
On admission	28.6 ± 1.5	23.2 ± 0.8	N/A
On study day	24.7 ± 1.5	21.1 ± 1.3
Diagnoses	Sepsis (3)	Sepsis (3)	N/A
	Pneumonia (3)	Pancreatitis (2)
	Severe asthma (1)	Head trauma (2)
	MVA (1)	MVA (3)
	Angioedema (1)	Cardiac failure (2)
	Sub-arachnoid	Burn (1)
	haemorrhage (1)	Lung abscess (1) Meningitis (1)

MVA: Motor Vehicle Accident.

^aP < 0.05 vs healthy subjects;

^cP < 0.05 vs healthy subjects and non-diabetic critically ill patients.

Table 2 Comparison of proximal gastric motor activity between critically ill patients and healthy subjects

	Diabetic ICUpatients(n = 10)	Non-diabeticICU patients(n = 15)	Healthysubjects(n = 10)
MDP (mmHg)	11.9 ± 1.0 a	11.3 ± 1.2 a	7.1 ± 0.6
Baseline intra-gastric volume (mL)	187 ± 43	197 ± 22	182 ± 19
Time to recovery of baseline volume following infusion (min)	41 ± 15 a	83 ± 11 c	15 ± 4

^aP < 0.05 vs healthy subjects;

^cP < 0.05 vs diabetic patients and healthy subjects.