pRB expression in esophageal mucosa of individuals at high risk for squamous cell carcinoma of the esophagus

Table 1 Relationship between pRB expression and demographic characteristics of the subjects at risk for ESCC

Characteristics	pRB – (%)	pRB + (%)	Total	P
Age (yr)
Under 50	10 (22.7)	34 (77.3)	44
Over 50	23 (18.3)	103 (81.7)	126	NS
Race
Caucasian	31 (20.0)	124 (80.0)	155
Others	2 (13.3)	13 (86.7)	15	NS
Family history of cancer
negative	12 (11.9)	89 (88.1)	101 (59.4)
positive	21 (30.4)	48 (69.6)	69 (41.6)	0.005

NS: non-significative.

Table 2 Odds ratio (OR) for loss of pRB expression by logistic regression

Feature	OR	95% CI	P
Familial history of cancer	3.83	1.62-9.04	0.0021
Age	1.28	0.52-3.15	NS
Race	0.72	0.15-3.52	NS
Histology	3.98	0.90-17.4	NS
Lugol staining	NS	NS	NS

NS: non-significative.