Rectal carcinosarcoma: A case report and review of literature

Table 1 Immunohistochemical profile of the tumor

marker	carcinomatous	sarcomatous
Cam 5,2	+	-
MNF 116	+	-
Vimentin	-	+
Actin	-	+
S 100	-	-
Chromogranin	-	-
c Kit	-	-
CD 34	-	-
HER2/neu	-	-
Ki 67	-	-
P53	+	-

Table 2 Cases of colonic carcinosarcoma reported in the English literature

Case	Author	Age/Sex	Location	Histology	TNM Stage	Recurrence	Adjuvant	Survival (Mo)
1	Weidner (1986)	73/M	Sigmoid	SCC+AC+OS+CS	II	Liver, LN, pelvis	Postop 5-FU, mitomycin C cyclophosphamide, doxorubicin, cisplatin	49, died
2	Chetty (1993)	72/F	Cecum	AC + UDSCS +RMS	IV	?	No	3, lost
3	Roncaroli (1995)	71/F	Anorectum	NEC + RMS	II	Pelvis	Preop radiotherapy	6, died
4	Takeyoshi (2000)	82/M	Anorectum	AC + UDSCS	II	Skin	No	6,died
5	Nakao (1998)	60/F	Transverse	AC + RMS	III	-	Postop 5-FU+cisplatin	14, disease free
6	Ishida (2003)	80/F	rectosigmoid	AC+SCSM-N	III	Pelvis	No	6, died
7	Aramendi (2003)	84/M	Splenic flexure	AC+OS+CS	II	-	No	Died at diagnosis
8	Present case	60/M	Rectum	AC+SCSM	III	Liver, Lung, pelvis, LN, peritoneum	Postop 5-FU, leucovorin and radiotherapy	6, died

SCC: squamous cell carcinoma, AC: adenocarcinoma, OS: osteosarcoma, CS: chondrosarcoma, UDSCS: undifferentiated spindle cell sarcoma, RMS: rhabdomyosarcoma, NEC: neuroendocrine carcinoma, SCSM: spindle cell sarcoma with muscular features, SCSM-N: spindle cell sarcoma exhibiting both muscular and neural features, LN: lymph nodes, postop: postoperative, preop: preoperative