Ductular proliferation in liver tissues with severe chronic hepatitis B: An immunohistochemical study

Table 1 Average optical density of typical and atypical ductular cells for CK8, CK19 and OV6 staining

Cell Types	Fields	CK8	CK19	OV6
Typical	8	0.402 ± 0.083	0.902 ± 0.355	0.324 ± 0.121
Atypical	9	0.998 ± 0.238b	0.371 ± 0.105b	0.752 ± 0.210

^bP < 0.001 vs typical

Table 2 Morphometric parameters of hepatic oval cells, hepatocyte-like cells and hepatocytes

Cell types	Cell numbers	At(µm2)	Dmax(µm)	Dmax/Dmin ratio
Hepaticovalcells	97	19.5 ± 5.9	12.4 ± 7.4	1.8 ± 0.5
Hepatocyte-likecells	42	32.1 ± 6.3b	18.9 ± 7.8b	1.2 ± 0.1
Hepatocytes	114	41.5 ± 2.3	24.7 ± 5.1	1.1 ± 0.1

^bP < 0.001 vs hepatic oval cells and hepatocytes