Solmi L, Nigro G, Roda E. Therapeutic effectiveness of echo-guided percutaneous radiofrequency ablation therapy with a LeVeen needle electrode in hepatocellular carcinoma. World J Gastroenterol 2006; 12(7): 1098-1104 [PMID: 16534852 DOI: 10.3748/wjg.v12.i7.1098]
Corresponding Author of This Article
Luigi Solmi, M.D., Unità Operativa di Gastroenterologia, Policlinico Sant’Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy. solmil@aosp.bo.it
Article-Type of This Article
Rapid Communication
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World J Gastroenterol. Feb 21, 2006; 12(7): 1098-1104 Published online Feb 21, 2006. doi: 10.3748/wjg.v12.i7.1098
Table 1 Characteristics of 56 cirrhotic patients with HCC treated with RFA
Parameters
Numbers
Total patients
56
Gender
Male
37
Female
19
Age (yr)
Range
45-81
Mean
68.7
Type of cirrhosis
Viral HCV-related
48
Viral HBV-related
3
Alcoholic
4
Autoimmune
1
Child-Pugh classification
A
16
B
37
C
3
Table 2 Characteristics of HCCs in 56 cirrhotic patients treated with RFA
Parameters
Numbers
Number of HCCs
63
One HCC
50
Two HCCs
5
Three HCCs
1
Type of HCCs
Nodular
63
Infiltrating
0
HCC diameter (cm)
> 1 < 2
19
> 2 < 3
27
> 3 < 4
12
> 4 < 5
5
Mean
2.8
Table 3 Clinical findings in 23 cirrhotic patients with HCC recurrence after RFA
Parameters
Numbers
Total patients
23
Time of recurrence (mo)
Range
3-30
Mean
13
Type of recurrence, n (%)
Local unifocal
2 (8.6%)
Different segments unifocal
5 (21.8%)
Different segments multifocal
16 (69.6%)
Treatment of recurrences
RFA
7 (unifocal)
TACE
5 (multifocal)
Supportive treatment
11 (multifocal)
Results of treatment
RFA
Complete necrosis 7/7
TACE
Complete necrosis 1/5
Table 4 Clinical findings in 32 deceased cirrhotic patients treated with RFA for HCC
Causes of death
Number of patients
Child-Pugh status
A
B
C
HCC recurrence
15
4
12
Liver failure
11
9
2
Esophageal varices
3
3
bleeding
Head stroke
1
1
Brain hemorrhage
1
1
Esophageal cancer
1
1
Citation: Solmi L, Nigro G, Roda E. Therapeutic effectiveness of echo-guided percutaneous radiofrequency ablation therapy with a LeVeen needle electrode in hepatocellular carcinoma. World J Gastroenterol 2006; 12(7): 1098-1104