Inhibition of hepatitis B virus expression and replication by RNA interference in HepG2.2.15

Table 1 Effect of pGenesil-siHBV X on HBsAg and HBeAg expression transfected HepG2.2.15 cells

Group	HBsAg (g/L)			HBeAg (Ncu/mL)
	24 h	48 h	72 h	24 h	48 h	72 h
Untreated	7.13 ± 0.20	14.43 ± 0.56	22.50 ± 2.14	0.43 ± 0.02	0.75 ± 0.06	1.12 ± 0.10
Metafectene	6.80 ± 0.17	13.57 ± 0.88	21.84 ± 0.91	0.48 ± 0.02	0.69 ± 0.08	1.03 ± 0.06
pGenesil	6.57 ± 0.40	14.30 ± 0.47	24.15 ± 2.24	0.45 ± 0.06	0.64 ± 0.05	1.00 ± 0.06
PGenesil-HK	6.47 ± 0.20	13.63 ± 0.64	21.84 ± 0.51	0.46 ± 0.05	0.69 ± 0.07	0.97 ± 0.08
PGenesil-AFP	6.33 ± 0.35	13.70 ± 0.73	23.11 ± 1.25	0.47 ± 0.05	0.76 ± 0.08	1.10 ± 0.12
PGenesil-HBVX	5.97 ± 0.13	10.25 ± 0.32b	15.26 ± 0.88b	0.43 ± 0.02	0.46 ± 0.01c	0.64 ± 0.04c

^bP < 0.01 vs untreated control and other controls;

^cP < 0.05 vs untreated control and other controls.