Copyright
©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 28, 2006; 12(36): 5798-5804
Published online Sep 28, 2006. doi: 10.3748/wjg.v12.i36.5798
Published online Sep 28, 2006. doi: 10.3748/wjg.v12.i36.5798
Table 1 Effect of BPB on gastric secretion and acidity in 6 h pylorus ligated rats (mean ± SE)
Table 2 Effect of BPB on ethanol induced changes in Alcian blue binding capacity, NP-SH levels and MPO activity in gastric mucosa of rats (mean ± SE)
Treatment | Alcian blue binding(mg/g tissue) | Non-proteinsulfhydryl(mmol/g tissue) | Myeloperoxidaseactivity(△A/g tissue) |
Normal | 935 ± 60.5 | 4.26 ± 0.11 | 0.081 ± 0.019 |
Ethanol (EtOH) alone | 688 ± 25.2a | 2.96 ± 0.22b | 0.974 ± 0.067b |
EtOH + BPB 5 mg/kg | 847 ± 75.8 | 4.08 ± 0.12d | 0.123 ± 0.024d |
EtOH + BPB 15 mg/kg | 820 ± 70.6 | 4.02 ± 0.24d | 0.186 ± 0.089d |
EtOH + BPB 45 mg/kg | 927 ± 34.2c | 4.80 ± 0.19d | 0.067 ± 0.025d |
- Citation: Tariq M, Elfaki I, Khan HA, Arshaduddin M, Sobki S, Moutaery MA. Bromophenacyl bromide, a phospholipase A2 inhibitor attenuates chemically induced gastroduodenal ulcers in rats. World J Gastroenterol 2006; 12(36): 5798-5804
- URL: https://www.wjgnet.com/1007-9327/full/v12/i36/5798.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i36.5798