Prevalence of H pylori associated ‘high risk gastritis’ for development of gastric cancer in patients with normal endoscopic findings

doi:10.3748/wjg.v12.i34.5509

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 12, Issue 34

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3213)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-4) series.

Item

Count

PDF

312

HTML

2390

Figures (1-2)

258

Tables (1-4)

253

Sum=3213

Sep 14, 2006 (publication date) through Feb 27, 2025

Times Cited of This Article

Times Cited (14)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Rapid Communication

World J Gastroenterol. Sep 14, 2006; 12(34): 5509-5512
Published online Sep 14, 2006. doi: 10.3748/wjg.v12.i34.5509

Table 1 Age and sex distribution of H pylori positive patients without gross pathology of gastric mucosa during upper GI-endoscopy

	*Endoscopic normal gastric mucosawith H pylori* infection**
Number (n)	845
Mean age (yr)	54.8 (18-87)
Sex
Male	450/845 (53.2%)
Female	395/845 (46.8%)
Age (yr)
< 35	114/845 (13.5%)
35-44	120/845 (14.2%)
45-54	151/845 (17.9%)
55-64	199/845 (23.6%)
65-74	166/845 (19.6%)
> 75	95/845 (11.2%)

Table 2 Frequency of intestinal metaplasia (IM) in the gastric antrum and the corpus in patients without macroscopic pathology during upper GI-endoscopy

Age (yr)	Overall IM	IM only inthe antrum	IM only in thecorpus	IM in antrumand corpus
< 35	9/114 (7.9%)	1/114 (0.9%)	7/114 (6.1%)	1/114 (0.9%)
35-44	14/120 (11.7%)	2/120 (1.7%)	12/120 (10.0%)	0/120 (0.0%)
45-54	28/151 (18.5%)	7/151 (4.6%)	18/151 (11.9%)	3/151 (2.0%)
55-64	50/199 (25.1%)	7/199 (3.5%)	35/199 (17.6%)	8/199 (4.0%)
64-75	65/166 (39.2%)	6/166 (3.6%)	51/166 (30.7%)	8/166 (4.8%)
> 75	38/95 (40.0%)	6/95 (6.3%)	24/95 (25.2%)	8/95 (8.4%)
Differences between age groups	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)

Table 3 Frequency of severe atrophy, antrum- and corpus-gastritis score in H pylori positive patients in different age-groups in patients without macroscopic pathology during upper GI-endoscopy

Age (yr)	Severe atrophy	Antrum gastritisscore	Corpus gastritisscore
< 35	0/114 (0.0%)	3.36 ± 0.90	2.49 ± 1.17
35-44	2/120 (1.7%)	3.17 ± 0.86	2.73 ± 1.02
45-54	3/151 (2.0%)	3.32 ± 1.04	2.85 ± 1.04
55-64	4/199 (2.0%)	3.38 ± 0.94	2.93 ± 1.17
64-75	9/166 (5.4%)	3.20 ± 0.92	2.98 ± 1.08
> 75	9/95 (11.2%)	3.08 ± 0.96	3.06 ± 1.15
Differences between age groups	P < 0.001 (χ²-test)	NS (ANOVA)	P < 0.001 (ANOVA)

Table 4 Comparison of gastric cancer risk index and phenotype of gastritis in 845 patients with H pylori positive gastritis

Phenotype of gastritis	Gastric cancer risk index
Phenotype of gastritis	0 point	1 point	2 points	3 points
Antrum-predominant gastritis	156	104	21	0
Pangastritis	107	178	113	36
Corpus-predominant gastritis	2	22	62	44

Citation: Leodolter A, Ebert MP, Peitz U, Wolle K, Kahl S, Vieth M, Malfertheiner P. Prevalence of H pylori associated ‘high risk gastritis’ for development of gastric cancer in patients with normal endoscopic findings. World J Gastroenterol 2006; 12(34): 5509-5512
URL: https://www.wjgnet.com/1007-9327/full/v12/i34/5509.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i34.5509