Liu YM, Qin H, Wang CB, Fang XH, Ma QY. Comparison of therapeutic effectiveness of combined interventional therapy for 1126 cases of primary liver cancer. World J Gastroenterol 2006; 12(31): 5060-5063 [PMID: 16937507 DOI: 10.3748/wjg.v12.i31.5060]
Corresponding Author of This Article
Ya-Min Liu, Department of Interventional Medicine, First Hospital, Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China. super2000haohao@163.com
Article-Type of This Article
Rapid Communication
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World J Gastroenterol. Aug 21, 2006; 12(31): 5060-5063 Published online Aug 21, 2006. doi: 10.3748/wjg.v12.i31.5060
Table 1 Clinical data of 1126 patients
Group
Cases(n)
Size of tumor (cm)
Clinical staging
Liver function level
< 5
5-10
> 10
I
II
III
A
B
C
Preop. TACE
258
20
145
93
104
154
0
155
103
0
Postop.TACE
154
9
76
69
16
138
0
83
71
0
TACE + RFA
126
3
57
66
48
57
21
92
34
0
TACE
469
31
239
199
156
251
62
252
197
20
TAI
119
11
47
61
28
47
44
14
73
32
Total
1126
74
564
488
352
647
127
596
478
52
Table 2 Clinical data of 1126 patients
Group
Cases(n)
Karnofsky scores
HBsA
AVF
Embolus in PV
0-80
80-100
(+)
HV
PV
Right
Left
Preop. TACE
258
172
86
221
9
19
67
73
Postop.TACE
154
98
56
124
4
10
21
16
TACE + RFA
126
83
43
107
12
27
32
26
TACE
469
291
178
412
76
125
106
92
TAI
119
78
41
101
22
34
32
28
Total
1126
722
404
965
123
215
258
235
Table 3 Accumulated survival rate for 874 HCC patients after various kinds of interventional therapy
Group
Cases(n)
1 yr
3 yr
5 yr
Cases(n)
Survivalrate (%)
Cases(n)
Survivalrate (%)
Cases(n)
Survivalrate (%)
Preop. TACE
198
148/198
74.7
82/198
41.4
58/157
36.9
Postop.TACE
114
90/114
78.9
46/114
40.4
33/88
37.5
TACE + RFA
106
79/106
74.5
39/106
36.8
-
-
TACE
387
268/387
69.3
84/387
21.7
26/309
8.4
TAI
69
8/69
11.6
0/69
0
0/69
0
Total
874
593/874
67.8
251/874
28.7
117/623
18.8
Table 4 Therapeutic effect of TACE+RAF, TACE and TAI in 562 patients
Group
Cases (n)
PR
NC
PD
Effective rate (%)
TACE + RFA
106
73
26
7
93.4
TACE
387
276
46
65
83.2
TAI
69
8
11
50
27.5
Total
562
357
83
122
81.5
Table 5 Changes of indexes before and after interventional therapy n (%)
Group
Index
Degrade ofChild liverfunction
Blackout ofblood flowinside tumor
Blackout ofblood flowaround tumor
RecoveryofAFP
TACE + RFA
33/106 (31.1)
59/106 (55.7)
54/106 (50.9)
49/106 (46.2)
TACE
119/387 (30.7)
212/387 (54.8)
189/387 (48.8)
174/387 (45.0)
TAI
23/69 (33.3)
0/69 (0)
0/69 (0)
0/69 (0)
Total
175/562 (31.1)
271/562 (48.2)
243/562 (43.2)
223/562 (39.7)
Citation: Liu YM, Qin H, Wang CB, Fang XH, Ma QY. Comparison of therapeutic effectiveness of combined interventional therapy for 1126 cases of primary liver cancer. World J Gastroenterol 2006; 12(31): 5060-5063