Role of neuronal nitric oxide synthase and inducible nitric oxide synthase in intestinal injury in neonatal rats

Table 1 Scores of lesion on distal ileum morphology of neonatal rats (mean ± SD, n = 8)

Score	Controlgroup	LPS group
		1 h	3 h	6 h	12 h	24 h
	0.12 ± 0.17	1.28 ± 0.62b	1.75 ± 0.74b	1.98 ± 0.75b	2.85 ± 0.41b	2.35 ± 0.63b
≥2 (n)	0	1	4	5	7	6

^aP < 0.05,

^bP < 0.01 vs control group.

Table 2 Optical density of nNOS and iNOS in ileum of neonatal rats (mean ± SD, n = 5)

Control group		LPS group
		1 h	3 h	6 h	12 h	24 h
nNOS	0.3987 ± 0.0020	0.3975 ± 0.0020	0.3965 ± 0.0020	0.3896 ± 0.0021b	0.3806 ± 0.0031c	0.3836 ± 0.0027c
iNOS	0.3806 ± 0.0080	0.3832 ± 0.0060	0.3869 ± 0.0050	0.3870 ± 0.0070	0.3968 ± 0.0101a	0.3812 ± 0.0070

^aP < 0.05,

^bP < 0.01,

^cP < 0.001 vs control group.

Table 3 nNOS mRNA and iNOS mRNA of ileum of neonatal rats (mean ± SD, n = 8)

	Control	LPS group
	group	1 h	3 h	6 h	12 h	24 h
nNOS	0.88 ± 0.23	0.72 ± 0.34	0.65 ± 0.32	0.39 ± 0.23b	0.47 ± 0.31a	0.64 ± 0.35
iNOS	0.70 ± 0.17	0.73 ± 0.19	0.75 ± 0.21	0.97 ± 0.23a	0.87 ± 0.29a	0.78 ± 0.22

^aP < 0.05,

^bP < 0.01 vs control group.