Transfusion-transmitted virus in association with hepatitis A-E viral infections in various forms of liver diseases in India

Table 1 Prevalence of TTV-DNA in different liver diseases

Liver disease	n	Presence of TTV-DNA
		n ( % )
Acute viral hepatitis	37	10 ( 27.0 )
Chronic viral hepatitis	37	7 ( 18.9 )
Cirrhosis	13	15 ( 48.4 )
Fulminant hepatic failure	32	3 ( 9.4 )
Control	100	27 ( 27.0 )

Table 2 Presence of TTV-DNA in relation to other viral hepatitis markers in liver diseases

	n ( % )
Liverdisease	n	TTV-DNA with	TTV-DNA with	TTV-DNA with
		HBsAg/IgM anti-HBc	anti-HCV/HCV-RNA	IgM anti-HEV
Acute viral hepatits	37	6 ( 16.2 )	0 ( NIL)	1 ( 2.7% )
Chronic viral hepatitis	37	5 ( 13.5 )	4 ( 10.8 )	-
Cirrhosis	31	10 ( 32.3 )	2 ( 6.5 )	-
Fulminant hepatic failure	32	0 ( NIL)	1 ( 3.2 )	0 ( NIL)

NIL: 0%. - : Not done, as HEV is not present in chronic and cirrhosis cases.

Table 3 Relation between TTV-DNA and ALT levels in different liver disease groups

Liverdisease	No. of TTV-DNA + patients	n ( % )[ALT (nkat/L)]
		833.5 - 3334	3335 - 6668	6669 - 10 002	>10 002
Acute viral hepatitis	10	6 (60)	3 ( 30)	0 ( NIL)	1 (10 )
Chronic viral hepatits	7	7 (100)	0 ( NIL)	0 ( NIL)	0 ( NIL)
Cirrhosis	15	14 (93.3)	1 ( 6.7)	0 ( NIL)	0 ( NIL)
Fulminant hepatic failure	3	0 ( NIL)	0 ( NIL)	0 ( NIL)	3 (100 )

Present value was computed in comparison to total number positive for TTV-DNA. Nil : 0%.