Chan KH, Chan CW, Chow WH, Kwan WK, Kong CK, Mak KF, Leung MY, Lau LK. Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong. World J Gastroenterol 2006; 12(14): 2223-2228 [PMID: 16610025 DOI: 10.3748/wjg.v12.i14.2223]
Corresponding Author of This Article
Dr. Kam Hoi Chan, Department of Medicine, Yan Chai Hospital, Tsuen Wan, Hong Kong SAR, China. kamhoichan@gmail.com
Article-Type of This Article
Clinical Research
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 2 Tumor characteristics of 47 patients with GISTs
n (%)
Number of patients
47
Median tumor size in cm (IRQ)
6.05 (3-7.5)
≤5 cm
24 (51)
>5-10 cm
13 (28)
>10 cm
4 (9)
Mitotic index
High
7 (15)
Low
18(38)
No
22(47)
Presence of distal metastasis or local invasion
7 (15)
Table 3 Univariate analyses of factors predicting GISTs recurrence or tumor related death
Prognostic factors
Hazard ratios
P value
Tumor size 5 cm or above
20.5
0.003
Presence of significant mitotic figures (1/10 HPF or above )
3.8
0.021
Presence of necrosis
4.4
0.005
Invasion to adjacent organ and/or presence of metastases at the time of diagnosis
16.5
<0.001
Incomplete tumor resection
4.6
0.002
Table 4 Multivariate analyses of factors predicting GISTs recurrence or tumor-related death
Prognostic factors
Hazard ratios (CI)
P value
Tumor size 5 cm or above
9.6 (1.1-86.0)
0.042
Invasion to adjacent organ and/or presence of metastases at the time of diagnosis
14.0 (2.5-78.6)
0.003
Incomplete tumor resection
2.1 (1.1-86.0)
0.032
Citation: Chan KH, Chan CW, Chow WH, Kwan WK, Kong CK, Mak KF, Leung MY, Lau LK. Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong. World J Gastroenterol 2006; 12(14): 2223-2228