Efficacy of different treatment strategies for hepatocellular carcinoma with portal vein tumor thrombosis

Table 1 Clinical characteristics of 179 HCC patients with PVTT.

Clinical characteristics	Conservative treatment (n = 18)	Chemo-therapy (n = 53)	Surgical resection (n = 24)	Surgical resection with chemotherapy (n = 84)	P
Gender					0.522
Male	15	49	20	76
Female	3	4	4	8
Age (yr)					0.51
<45	8	28	9	45
≥45	10	25	15	39
Child-Pugh Class					0.731
A	12	39	18	66
B	6	14	6	18
Tumor location					0.351
Left lobe	3	6	5	22
Right lobe	10	33	13	51
Left and right lobe	4	13	6	9
Caudate lobe	1	1	0	2
Tumor size					0.43
<10 cm	6	25	13	45
≥10 cm	12	28	11	39
Tumor number					0.715
1	11	33	14	58
≥2	7	20	10	26
Tumor thrombus location					0.639
Left branch	3	7	4	18
Left branch extending	1	2	2	7
to main trunk
Right branch	6	23	12	41
Right branch extending	4	10	4	11
to main trunk
Left, right branch and main trunk	4	11	2	7

Table 2 Survival periods and rates of different groups.

Groups	Mean survival periods (mo)	0.5-yr survival rate (%)	1-yr survival rate (%)	2-yr survival rate (%)	3-yr survival rate (%)
Conservative treatment	3.6	5.5	0	0	0
Chemotherapy	7.3	34.6	11.8	0	0
Surgical resection	10.1	46.8	22.7	9.8	0
Surgical resection with chemotherapy	15.1	55.8	39.3	30.4	15.6

Table 3 Variables influencing postoperative survival of patients with HCC and PVTT.

Influent variables	Survival periods (mo) mean±SD	P
Tumor size
<10 cm	19.2±3.26	0.037
≥10 cm	12.8±2.47
Number of chemotherapy cycles
0	8.6±1.68	0.006
1	11.9±2.24
2	16.7±2.98
≥3	23.1±4.32