Transforming growth factor beta can be a parameter of aggressiveness of pT1 colorectal cancer

Table 1 TGF β expression in main mass of CRC with and without vascular invasion.

Parameter	Expression of TGF β, n (%)		Positive	Total (%)
	n	Negative
With vascular invasion	14	3 (21.4)	11 (78.6)	41.2
Without vascular invasion	20	14 (70)	6 (30)	58.8

P = 0.005, P<0.01.

Table 2 TGF β expression in main mass of CRC with and without lymph node metastasis.

Parameter	Expression of TGF β, n (%)		Positive	Total (%)
	n	Negative
With lymph node metastasis	16	2 (12.5)	14 (87.5)	47.1
Without lymph node metastasis	18	15 (83.3)	3 (16.7)	52.9

P = 0.0001, P<0.01.

Table 3 TGF β expression in main mass of CRC with and without distant metastasis.

Parameter	Expression of TGF β, n (%)		Positive	Total (%)
	n	Negative
With distant metastasis	14	1 (7.2)	13 (92.8)	41.2
Without distant metastasis	20	16 (80.0)	4 (20.0)	58.8

P = 0.00003, P<0.01.

Table 4 TGF β expression in main mass of CRC with and without tumor budding.

Parameter	Expression of TGF β, n (%)		Positive	Total (%)
	n	Negative
With tumor budding	12	1 (8.3)	11 (91.7)	35.3
Without tumor budding	22	16 (72.7)	6 (27.3)	64.7

P = 0.00003, P<0.01.