Decreased expression of type II tumor suppressor gene RARRES3 in tissues of hepatocellular carcinoma and cholangiocarcinoma

Table 1 Characteristics of cancer patients and tissues.

Categories	Number of cases
Cholangiocarcinoma
M/F	9/12
Average age (yr)	67.0±8.1
Stages
I	2
II	9
III	8
IV	2
Tumor differentiation
Well	10
Moderate	7
Poor	4
Hepatocellular carcinoma
M/F	24/6
Average age	53.9±15.0
Tumor differentiation
Well	4
Moderate	23
Poor	3
Stages
I	4
II	18
III	1
NA1	7

¹Not available.

Table 2 Expression of RIG1 protein in CC tissues.

Categories	RIG protein staining[n (%) of cases]		Fisher's exact test
	Negative	Positive
Differentiation			P<0.01
Well	2 (20.0)	8 (80.0)
Moderate/poor	9 (81.8)	2 (18.2)
Stages			P = 0.40
I and II	7 (63.6)	4 (36.4)
III and IV	4 (40.0)	6 (60.0)

Table 3 Expression of RIG1 protein in HCC tissues.

Tissues	RIG1 protein [n (%) of cases]
	Negative	Positive
Adjacent normal	5(16.7)	25(83.3)
HCC	13(43.3)	17(56.7)

Logistic regression analysis: OR = 0.27, 95% CI (0.11–0.62), P<0.01.