Effects of killing Helicobacter pylori quadruple therapy on peptic ulcer: A randomized double-blind clinical trial

Table 1 Data on enrolled cases (%, mean±SD).

	Group A (n = 25)	Group B (n = 28)	Group C (n = 15)
Sex
Male	21 (84.0)	23 (82.1)	13 (86.7)
Female	4 (16.0)	5 (17.9)	2 (13.3)
Age (yr)	41.6±1.2	43.2±2.4	38.8±1.8
Height (cm)	169±4.6	166.1±7.9	166.5±7.5
Weight (kg)	64.4±8.1	62.3±9.6	60.2±6.9
Disease course (yr)	4.2±3.8	4.2±4.0	4.2±3.7
Gastric ulcer	5 (20.0)	8 (28.6)	4 (26.7.0)
Duodenal ulcer	20 (80.0)	20 (71.4)	11 (73.3)
Diameters (cm)	1.0±0.5	1.0±0.4	1.0±0.4
Smoking	16 (64.0)	18 (64.3)	9 (60.0)
Alcohol drinking	9 (36.0)	10 (35.7)	5 (33.3)
Upper abdominal pain	23 (92.0)	27 (96.4)	14 (93.3)
Distension	16 (64.0)	16 (57.1)	10 (66.7)
Heart burn or acid reflux	16 (64.0)	16 (57.1)	9 (60.0)
Belch	8 (32.0)	9 (32.1)	5 (33.3)
Inappetence	10 (40.0)	11 (39.3)	6 (40.0)
Constipation	9 (36.0)	10 (35.7)	5 (33.3)

Table 2 Healing rate of PU.

Group	Healed (%)	Improved (%)	Unimproved (%)	Total (%)
A (n = 25)	22 (88.0)a	3 (12.0)		100
B (n = 28)	28 (100.0)a	0		100
C (n = 15)	3 (20.0)	4 (26.7)	8 (53.3)	46.7

^aP<0.005 vs group C.

Table 3 Histology of regenerating mucosae of healed ulcers.

Group	Good (%)	Fair (%)	Poor (%)
A (n = 17)	7 (41.2)	10 (58.8)	0 (0.0)a
B (n = 18)	16 (88.9)	2 (11.1)	0 (0.0)bc
C (n = 3)	0 (0.0)	1 (33.3)	2 (66.7)

^aP<0.05,

^bP<0.01 vs group C;

^cP<0.05 vs group A.