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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 28, 2005; 11(48): 7671-7675
Published online Dec 28, 2005. doi: 10.3748/wjg.v11.i48.7671
Published online Dec 28, 2005. doi: 10.3748/wjg.v11.i48.7671
Table 1 SC6-Ag levels in patients with malignant and benign disease
| >41 U/mL | >80 U/mL | >118 U/mL | ||
| Groups | Cases | |||
| n(%) | n (%) | n (%) | ||
| Control | 102 | 7 (6.9) | 2 (2.0) | 0 ( 0.0) |
| Pancreatic Ca | 115 | 84 (73.0) | 68 (59.1 ) | 56 (48.7) |
| Digestive Ca | 154 | 46 ( 29.9) | 24 (15.6 ) | 11 (7.1 ) |
| Non-digestive Ca | 95 | 11 (11.6) | 8 (8.4 ) | 4 (4.2) |
| Benign digestive | ||||
| Diseases | 140 | 13 (9.3) | 9 (6.4 ) | 2 (1.4) |
| Non-benign digestive |
Table 2 SC6-Ag concentration in ascites from patients with different digestive diseases (mean±SD)
| >41 | >80 | >118 | |||
| Groups | Cases | SC6-Ag (U/mL) Concentration | n (%) | n ( %) | n (%) |
| Pancreatic Ca | 16 | 120.9±109.1 | 15 (93.8) | 11 (68.8) | 7 (43.8) |
| Hepatic Ca | 19 | 55.7±33.4 | 10 (52.6) | 3 (15.8) | 1 (5.3) |
| Colonic Ca | 16 | 54.9±36.7 | 9 (56.3) | 4 (25.0) | 1 (6.3) |
| Gastric Ca | 10 | 38.1±23.4 | 3 (30.0) | 1 (10.0) | 0 (0.0) |
| Several pancreatitis | 6 | 30.9±26.3 | 2 (33.3) | 0 (0.0 ) | 0 (0.0) |
Table 3 Comparison of parameters for SC6-Ag, CA19-9, ultrasound and CT in patients with pancreatic cancer
| SC6-Ag(%) | CA19-9(%) | Ultrasound(%) | CT(%) | |
| Sensitivity | 73.0 (84/115) | 84.3 (97/115) | 82.6 (95/115) | 83.5 (96/115) |
| Specificity | 90.9 (70/77) | 84.4 (65/77) | 55.8 (43/77) | 59.7 (46/77) |
| Positive predictive value | 92.3 (84/91) | 88.5 (92/104) | 73.8 (96/130) | 76.2 (99/130) |
| Negative predictive value | 69.3 (70/101) | 73.9 (65/88) | 69.4 (43/62) | 74.2 (46/62) |
- Citation: Liu MP, Guo XZ, Xu JH, Wang D, Li HY, Cui ZM, Zhao JJ, Ren LN. New tumor-associated antigen SC6 in pancreatic cancer. World J Gastroenterol 2005; 11(48): 7671-7675
- URL: https://www.wjgnet.com/1007-9327/full/v11/i48/7671.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i48.7671