Gastric Cancer
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2005; 11(47): 7405-7412
Published online Dec 21, 2005. doi: 10.3748/wjg.v11.i47.7405
Table 1 Up-regulated genes noted in gastric cancer
Biosynthesis
Argininosuccinate synthetase [BC009243], hydroxymethylbilane synthase [BC000520], hypothetical protein CL640 [BC008804], methylenetetrahydrofolate dehydrogenase (NADP+-dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase [BC001014]
Cell adhesion
Collagen, type XVIII, alpha 1 [AF01808], mesothelin [U40434], CD9 antigen (p24) (X60111), collagen, type VI, alpha 3 [X52022], thrombospondin 2 [L12350], immunoglobulin superfamily containing leucine-rich repeat [AB003184]
Cell death
Nerve growth factor receptor (TNFR superfamily, member 16) [M14764], phosphoprotein enriched in astrocytes 15 [AF153274], programmed cell death 5 [AF014955]
Cell growth and/or maintenance
Cell division cycle 25B [S78187], cyclin D2 [D13639], hippocalcin [BC001777], anillin, actin binding protein (scraps homolog, Drosophila) [AF273437], afamin [L32140], chromosome 14 open reading frame 58 [AK000378], C1q and tumor necrosis factor related protein 1 [AF32984], low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [D86407], enhancer of rudimentary homolog (Drosophila) [U66871], tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) [D11139], insulin receptor substrate 2 [AF073310], low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [D50678], thyroid hormone receptor interactor 10 [AJ000414], collagen, type I, alpha 1 [Z74615], ATPase, Na+/K+ transporting, beta 3 polypeptide [AF005896], T-LAK cell-originated protein kinase [AB027249], platelet-derived growth factor receptor, beta polypeptide [J03278], nucleolar protein 1 120 ku [BC000656], keratin 7 [BC002700], oncostatin M receptor [BC010943], tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) [BC000866], insulin-like growth factor 2 (somatomedin A) [S77035], karyopherin (importin) beta 1 [L38951], nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15) [X07315], nucleolar protein 1 120ku [X55504], thymosin beta-10 [S54005]
Cell motility
Hyaluronan-mediated motility receptor (RHAMM) [AF03286], sorcin [M32886], troponin T1, skeletal, slow [BC010963]
Cell-cell signaling
Ephrin-A2 [U92896], midkine (neurite growth-promoting factor 2) [X55110], prostaglandin I2 (prostacyclin) receptor (IP) [D25418]
Immune response
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) [X14831], Human 1-8D gene from interferon-inducible gene family [X57351], GTP binding protein over-expressed in skeletal muscle [U10550], indoleamine-pyrrole 2,3 dioxygenase [M34455], interferon induced transmembrane protein 1 (9-27) [J04164]
Macromolecule metabolism
Cathepsin L2 [AB001928], PAK2 [AF09213], ribosomal protein, large P2 [M17887], hypothetical protein FLJ22761 [AK026414], KIAA0205 [D86960], proteasome (prosome, macropain) subunit, alpha type, 1 [D00759], protein tyrosine phosphatase type IVA, member 1 [U48296], peptidylprolyl isomerase (cyclophilin)-like 1 [BC003048], ribosomal protein L14 [BC009294], pyruvate kinase, muscle [BC007952], proteasome (prosome, macropain) subunit, alpha type, 7 [BC001895], isocitrate dehydrogenase 3 (NAD+) alpha [U07681], transglutaminase 4 (prostate) [U31905]
Organogenesis
Secreted protein, acidic, cysteine-rich (osteonectin) [M25743], caudal type homeo box transcription factor 2(CDX2) [AJ278434], transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) [M36711]
Regulation of metabolism
Homeo box B7 [BC015345], B-cell receptor-associated protein 37 [AF126021], Mediterranean fever [AJ003147], homeo box B7 [M16937], homeo box D4 [X17360], TIP49 [AB012122], sin3-associated polypeptide, 18 ku [AF153608]
Response to stress
Complement component 2 [X04481], complement component 3 [K02765], inhibin, beta A (activin A, activin AB alpha polypeptide) [X57579], serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 [K02212], serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) [D83174], meiotic recombination (S. cerevisiae) 11 homolog A [AF073362], RecQ protein-like 4 [BC013277]
Signal transduction
Secreted frizzled-related protein 4 [AF026692], lymphocyte antigen 6 complex, locus E(RIG-E) [Z68179], dimethylarginine dimethylaminohydrolase 2 [BC001435]
Unclassified
Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [BI826471], apolipoprotein C-I [AV709433], argininosuccinate synthetase [BF305206], ATPase, Ca++ transporting, plasma membrane 4 [AI885833], ATPase, Na+/K+ transporting, beta 3 polypeptide [AU151263], B-cell associated protein [BG771222], BTG family, member 2 [BG750101], cadherin 3, type 1, P-cadherin (placental) [NM001793], calcium modulating ligand [AW474551], carbonyl reductase 3 [AI658832], cathepsin Z [AI913006], CDC-like kinase 2 [BG286233], cell division cycle 25B [BF976307], CGI-01 protein [AK027886], chloride intracellular channel 1 [AA291390], claudin 4 [BI760179], claudin 7 [AI279608], collagen, type I, alpha 1 [AW577407], collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia) [NM000493], core-binding factor, beta subunit [NM001755], D123 gene product [BE792735], deoxythymidylate kinase (thymidylate kinase) [BF312526], diubiquitin [AW270961], DKFZP566C134 protein [BG621382], E2F transcription factor 3 [AU153511], epithelial protein lost in neoplasm alpha [AAF23756], exostoses (multiple) 1 [BF057267], FK506-binding protein 4 (59 ku) [NM002014], follistatin-like 3 (secreted glycoprotein) [NM005860], forkhead box M1 [AL525810], glutamine-fructose-6-phosphate transaminase 2 [AK001242], GTP-binding protein over-expressed in skeletal muscle [AW297828], guanylate cyclase 2C (heat stable enterotoxin receptor) [NM004963], heme oxygenase (decycling) 1 [BI596354], HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 [BG167159], Homo sapiens cDNA FLJ11796 fis, clone HEMBA1006158, highly similar to Homo sapiens transcription factor forkhead-like 7 [FKHL7] gene [BI914918], homo sapiens mRNA for short form of beta II spectrin, partial [AA131993], human cDNA: FLJ22528 fis, clone HRC12825 [AK026181], human cDNA: FLJ22998 fis, clone KAT11985, highly similar to AB000712 Human hCPE-R mRNA for CPE-receptor [AK026651], human chromosome 20 clone h119, complete sequence [AF312913], human claudin 3 [CLDN3] gene, [AF007189], regenerating islet-derived family, member 4 [AF254415], human genomic DNA, chromosome 22q11.2, clone KB1125A3 [AP000350], likely ortholog of mouse membrane bound C2 domain containing protein [AB018290], KIAA0930 protein [AB02314], hypothetical protein LOC90499 [AL137712], fuse-binding protein-interacting repressor [AF190744], Thy-1 cell surface antigen [M11749], biglycan [BC002416], CK2 interacting protein 1; HQ0024c protein [BC010149], hypothetical protein FLJ12436 [BC011993], tissue inhibitor of metalloprotease 1 (erythroid potentiating activity, collagenase inhibitor) [BC000866], hypothetical protein FLJ20277 [M11749], hypothetical protein FLJ22393 [H45848],hypothetical protein PRO1489 [AI536671], interferon induced transmembrane protein 1 (9-27) [BG506643], interferon induced transmembrane protein 3 (1-8U) [BE886918], interleukin 13 [NM002188], interleukin 8 [BG777366], JM4 protein [BI818455], keratin 7 [BI094014], keratin 7 [AA307373], KIAA0747 protein [BG744628], low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [BF110337], lymphocyte antigen 6 complex, locus E [BM101706], matrix metalloproteinase 7 (matrilysin, uterine) [NM002423], membrane protein of cholingeric synaptic vesicles [BG760616], mesothelin [AI813749], midkine (neurite growth-promoting factor) [AI784469], msh (Drosophila) homeo box homolog 1 [AI912103], MyoD family inhibitor [BG675569], neural precursor cell expressed, developmentally down-regulated 5 [AU131176], neuromedin U [BG661038], NIPSNAP, C. elegans, homolog 1 [BC006473], nucleolar and coiled-body phosphoprotein [AL553791], platelet-derived growth factor receptor, beta polypeptide [BI755841], procollagen-lysine, 2-oxogutarate 5-dioxygenase 3 [AL544817], proliferating cell nuclear antigen [AA523378], proliferation-associated 2G4, 38KD [BI088072], protein C receptor, endothelial (EPCR) [BG831881], pyruvate kinase, muscle [BF690275], rhoG [BG338917], regulatory factor X, 5 [AW027312], ribosomal protein L23 [AI349581], ribosomal protein L35 [BF310946], ribosomal protein L37 [BG032793], ribosomal protein S16 [BG765030], ribosomal protein S3 [AA593872], S100 calcium-binding protein A4 [AV713821], serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) [BG567810], sigma receptor (SR31747 binding protein 1) [AL571572], small inducible cytokine subfamily A (Cys-Cys), member 19 [W07401], superoxide dismutase 2, mitochondrial [BG773219], survival of motor neuron 1, telomeric [AA029190], thymosin, beta 10 [AV707021], thyroid hormone receptor interactor 10 [N98668], transKetolase [BI195990], translocase of outer mitochondrial membrane 34 [BE798732], trefoil factor 3 (intestinal) [AA633399], tumor suppressing subtransferable candidate 3 [BE670374], zinc finger protein 267 [AU128446]
Table 2 Down-regulated genes noted in gastric cancer
Biosynthesis
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [D89976], adenosine monophosphate deaminase 1 (isoform M) [M60092], histidine decarboxylase [D16583], Human histidine decarboxylase (HDC) [M60445]
Catabolism
Human bilirubin UDP-glucuronosyltransferase isozyme 1 [M57899], Human placental cDNA coding for 5’nucleotidase (EC 3.1.3.5) [X55740]
Cell adhesion
Collagen, type IV, alpha 6 [D21337], collagen, type XVII, alpha 1[U76585], tenascin C (hexabrachion) [X78565], dermatopontin [AL049455], Human pancreatitis associated protein [M84337], sialic acid binding Ig-like lectin 11 [AF337818], Macaque brain cDNA clone:QflA-14173, full insert sequence [AB062939]
Cell death
Baculoviral IAP repeat-containing 1 [U80017], CD3E antigen, epsilon polypeptide (TiT3 complex) [X03884], programmed cell death 4 (neoplastic transformation inhibitor) [U96628]
Cell growth and/or maintenance
Core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related [S69002], ATPase, Ca++ transporting, ubiquitous [Z69881], ATP-binding cassette, sub-family C (CFTR/MRP), member 5 [AB005659], B-cell CLL/lymphoma 3 [M31732], CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1 [AF015592], gastrokine 1 [AB039886], Human chondroadherin mRNA, complete cds [AF371328], CDC28 protein kinase regulatory subunit 2 [X54942], solute carrier family 39 (zinc transporter), member 6 [U41060], ATPase, H+/K+ exchanging, alpha polypeptide [M63962], golgi autoantigen, golgin subfamily a, 4 [U31906], ATPase, H+/K+ exchanging, beta polypeptide [M75110], solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 [AB037669], transcription factor-like 5 (basic helix-loop-helix) [AF070992], kinesin family member 11 [U37426], cholecystokinin B receptor [D13305], choline kinase alpha [D10704], sodium channel, nonvoltage-gated 1, gamma [X87160], MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) [D28480], sodium channel, nonvoltage-gated 1 alpha [X76180], oxysterol binding protein-like 7 [AF323729], zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) [AF060568], solute carrier organic anion transporter family, member 2A1 [U70867], aurora kinase B [AF004022], CDC-like kinase 1 [M59287], trefoil factor 1 [X52003], quiescin (Q6) [U97276], signal recognition particle receptor (‘docking protein’), clone MGC:1609 IMAGE:3528505, mRNA, complete cds [BC001162], villin-like, clone MGC:656 IMAGE:3356294, mRNA, complete cds. [BC000243], inhibitor of DNA binding 1, dominant negative helix-loop-helix protein [S78825], insulin-like growth factor binding protein 2 36 ku [S37730], Macaque somatostatin I mRNA, complete cds. solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) [S68616], platelet-derived growth factor receptor, alpha polypeptide [M21574], SH3-domain GRB2-like 2 [AF036268], solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) [M96067], thiosulfate sulfurtransferase (rhodanese) [BI820468], thrombomodulin [M16552]
Cell-cell signaling
NAD(P)H dehydrogenase, quinone 1 [J03934], dopamine receptor D5 [BC009748], monoamine oxidase A [M69226]
Digestion
Japanese Macaque (Macaca fuscata) mRNA for pepsinogen A-2/3. [X59755]
Electron transport
Cytochrome P450, family 4, subfamily F, polypeptide 12 [AY008841], cytochrome P450, family 2, subfamily C, polypeptide 18 [M61853], cytochrome P450, family 4, subfamily F, polypeptide 11 [AF23608], cytochrome P450, family 2, subfamily S, polypeptide 1 [AF33527], dual oxidase 1 [AF21346], cytochrome c oxidase subunit Vic [BC000187]
Immune response
Diacylglycerol kinase, delta 130 ku [D63479], Fc fragment of IgG, high affinity Ia, receptor for (CD64) [X14356], beta-site APP-cleaving enzyme 2 [AL163285], X-box binding protein 1 [L13850]
Macromolecule metabolism
Sphingomyelin phosphodiesterase, acid-like 3A [Y08136], calpain 9 (nCL-4) [AB038463], carboxypeptidase A2 (pancreatic) [BC007009], 2,4-dienoyl CoA reductase 2, peroxisomal [AE006463], protein kinase (cAMP-dependent, catalytic) inhibitor beta [AF225513], calpain 13 [AK027176], calpain 9 (nCL-4) [AF022799], fructose-1,6-bisphosphatase 1 [L10320], fructose-1,6-bisphosphatase [Y10812], gastric lipase [X05997], heat shock 10 ku protein [AJ250915], progastricsin (pepsinogen C) [M23077], protein tyrosine phosphatase, receptor type, N polypeptide 2 [U66702], carboxypeptidase A2 (pancreatic) [U19977], prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) [M59979], hyaluronoglucosaminidase 1 [U03056], galactose-4-epimerase, UDP-[L41668], chaperonin containing TCP1, subunit 3 (gamma)[BC008019], proprotein convertase subtilisin/kexin type 7 [BC010696], ubiquitin specific protease 14 (tRNA-guanine transglycosylase), [BC003556], Kallikrein 11 [AB013730], KIAA0089 protein [BC006168], prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) [S36219], prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) [U63846]
Metabolism
Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) [AB032150], alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide [X76342], carbonic anhydrase II [J03037], carbonic anhydrase IX [Z54349], transcription termination factor, mitochondrial [Y09615], hydroxyprostaglandin dehydrogenase 15-(NAD) [L76465], dehydrogenase/reductase (SDR family) member 9 [AY017349], sulfotransferase family, cytosolic, 1C, member 1 [AF186261], ribonuclease, RNase A family, 4 [BC015520]
Organogenesis
GATA binding protein 4 [L34357], aldehyde dehydrogenase 3 family, member A2 [U46689], tropomyosin 4 [BC002827]
Regulation of blood pressure
Chromogranin A (parathyroid secretory protein 1) [BC009384]
Regulation of coagulation
Annexin A10 [AJ238979]
Regulation of metabolism
Estrogen-related receptor gamma [AB020639], zinc finger protein 345 [X78933], Kruppel-like factor 2 (lung) [AF134053], RAR-related orphan receptor C [U16997], PEPP subfamily gene 2 [AL590526]
Response to stress
Checkpoint suppressor 1 [BC007506], CHK1 (checkpoint, S.pombe) homolog [AF016582], for protein disulfide isomerase-related [D49490], glutathione S-transferase A3 [BG573805], glutathione synthetase [AK000947], glutathione S-transferase A4-4 (GSTA4) [AF025887], cathepsin E (CatE gene), [AJ250716], glutathione peroxidase 3 (plasma) [D00632], RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) [D14134], RAD51 (S. cerevisiae) homolog C [BC000667]
Signal transduction
G protein-coupled receptor 30[U63917], hypothetical protein FLJ22595[AK026248], G protein-coupled receptor 30[AF015257], RAP1, GTPase activating protein 1[M64788], active BCR-related gene[U01147], G protein-coupled receptor, family C, group 5, member B[AL137684], G protein-coupled receptor, family C, group 5, member C[AF207989], RAS protein activator like 1 (GAP1 like)[AF086713], regulator of G-protein signaling 17 [RGS17] mRNA, complete cds. [AF202257], histidine triad nucleotide-binding protein, [BC007090], RAB26, member RAS oncogene family, [BC007681]
Unclassified
Actin binding LIM protein 1 [NM006719], activated leucocyte cell adhesion molecule [AI050952], adrenergic, beta-2-, receptor, surface [NM000024], alcohol dehydrogenase 1C (class I), gamma polypeptide[NM000669], aldehyde dehydrogenase 1 family, member A1 [AV649527], aldehyde dehydrogenase 3 family, member A2 (BF679509), aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) [BI759009], annexin A7 [NM004034], arylacetamide deacetylase (esterase) [L32179], ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42 ku [N75606], ATPase, H+/K+ exchanging, beta polypeptide [BI760752], ATP-binding cassette, sub-family C (CFTR/MRP), member 5 [NM005688], bA438B23.1 (neuronal leucine-rich repeat protein) [CAC22713], bB379O24.1 (novel protein similar to transcription factor GATA-5) [CAC36001], beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) [BE550952], calpain 2, (m/II) large subunit [BI771158], cathepsin E [AI598121], CDC28 protein kinase 2 [BG618998], chaperonin containing TCP1, subunit 2 (beta) [N98764], chromosome 1 open reading frame 8[BG476131], clathrin, light polypeptide (Lcb) (BE791502), cleavage and polyadenylation specific factor 5 25 ku subunit [AA738354], contactin 2 (axonal) [AI366526], cytochrome P450 isoform 4F12 [NM023944], cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9[BG567504], keratin 20 [X73501], delta sleep inducing peptide, immunoreactor [AL525317], DNA segment, numerous copies, expressed probes (GS1 gene) [AL570791], ESTs [AW960145], ESTs[N24233], ESTs, Highly similar to A32915 nucleophosmin [BG033160], ESTs, highly similar to AF078844 1 hqp0376 protein [BG165945], ESTs, Weakly similar to CA18 MOUSE COLLAGEN ALPHA 1(VIII) CHAIN PRECURSOR [M. musculus] [AW275800], ESTs, weakly similar to JC5314 CDC28/cdc2-like kinase associating arginine-serine cyclophilin [H. sapiens] [R85437], Fc fragment of IgG binding protein [D84239], flap structure-specific endonuclease 1 [BG773959], forkhead box O3A [AU134033], Friedreich ataxia region gene X123 [BI771919], galactose-4-epimerase, UDP-[BE388744], GATA-binding protein 6 [NM005257], glucosaminyl (N-acetyl) transferase 2, I-branching enzyme [NM001491], glutamic-pyruvate transaminase (alanine aminotransferase) [NM005309], glutathione S-transferase A4 [BI597618], granuphilin-a [BAA84656], hepatocyte nuclear factor 3, gamma [NM004497], highly expressed in cancer, rich in leucine heptad repeats [AA878068], holocytochrome c synthase (cytochrome c heme-lyase) [AL561481], Homer, neuronal immediate early gene, 2(BG742654), Homo sapiens clone 23763 unknown mRNA, partial cds [BG743005], homo sapiens SNC73 protein [SNC73] mRNA, complete cds[BF663123], homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 [BF966630], human (clone HUAB2-3) Ig mRNA, variable region, partial cds. [L19893], human [JER47] MUC5AC mRNA for mucin (partial). [Z34277], peroxisomal membrane protein 2 22 ku (AIBC1) [AF250136], breast carcinoma amplified sequence 1 (AIBC1) [AF041260], Human cDNA FLJ11341 fis, clone PLACE1010786. [AK002203], human cDNA: FLJ20990 fis, clone CAE01666.[AK024463], cell-type T-cell Ig gamma-chain, V region (IGHV@) [L03144], KFAL6 lambda 1 Ig light chain variable region [AF124182], hypothetical protein FLJ22795 [AF316855], defensin, theta 1 [U10267], immunoglobulin heavy diversity 2-21 [AB019441], Human gastric H,K-ATPase catalytic subunit gene, complete cds. [M63962], genomic DNA of 21q22.2 Down Syndrome region, segment 11/13. [AP000020], BIC transcript [AP001693], immunoglobulin kappa variable 1-8 [AP001209], genomic DNA, chromosome 8q23, clone:KB1747F8. [AP003113], glucocorticoid receptor alpha mRNA, variant 3’ UTR [U25029], immunoglobulin lambda constant 1 (Mcg marker) [D87023], Ig lambda light chain variable region gene (24-12ITIIIE213) rearranged; Ig-Light-Lambda; VLambda. [Z85038], Ig rearranged gamma chain mRNA, V-J-C region and complete cds. [M63438], Ig rearranged gamma chain mRNA, V-J-C region and complete cds. [M63438], metallothionein 1F (functional) [M13003], metallothionein 1A (functional) [K01383], mRNA for anti-Sm antibody VL chain (V kappa 4/J kappa 3). [Z46347], heat shock 70 ku protein 4 [AB023420], Ig heavy chain variable region, clone ToPA214. [Z98733], Ig kappa light chain, anti-RhD, therad 7. [AJ010422], Ig lambda light chain. [Y14738], sterile alpha and TIR motif containing 1 [AJ290445], KIAA0832 protein, complete cds.[AB020639], synaptotagmin-like 2 [AB046817], metallothionein 1L [X97261], NPC-related protein NAG73 [AF280797], prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) [AY008282], Human promyelocytic leukemia zinc finger protein (PLZF) gene, complete cds. [AF060568], cystatin A (stefin A) [X05978], sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F [U38276], serine protease inhibitor, Kazal type 1 [AF286028], SM22 alpha gene, 5’ flanking region. [D84344], hypothetical protein MGC27165 [AF067420], activating transcription factor 4 pseudogene (tax-responsive enhancer element B67 pseudogene) [U03712], chromosome 7 open reading frame 28B [BC010130], Human, clone MGC:2392 IMAGE:2961444, [BC001646], Human, LIM domain only 4, clone MGC:872 IMAGE:3355972, [BC003600], S100 calcium binding protein P [BC006819], Similar to Ig kappa constant, clone MGC:12418 IMAGE:3934658, [BC005332], hyaluronoglucosaminidase 1 [AL578077], hypothetical protein [AI202106], immunoglobulin heavy constant mu [BM008087], immunoglobulin heavy constant mu [AI634950], immunoglobulin lambda joining 3 [BF338816], immunoglobulin lambda locus [M87790], IMP (inosine monophosphate) dehydrogenase 1[AL518727], interleukin 1, beta [AA577318], karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [BE889289], KIAA0008 gene product [BI087140], KARP-1-binding protein [AB022659], KIAA0657 protein [BC007201], family with sequence similarity 13, member A1 [AF009202], glutamate receptor interacting protein 2 [AF052177], KIAA1727 protein [AB051514], Kruppel-like factor 4 (gut)[AI568487], lactotransferrin [BI021407], lamin B receptor [L25931], lethal giant larvae homolog 2 (Drosophila) [AK025401], leukemia inhibitory factor receptor [NM002310], lipase, gastric [NM004190], Macaque dd-4 gene for 3(20)alpha-hydroxysteroid/dihydrodiol dehydrogenase, complete cds. [AB020711], Macaque testis cDNA clone:QtsA-14970, full insert sequence. [AB070147], mammaglobin 2 [NM002407], membrane-bound transcription factor protease, site 2 [AU099021], metallothionein 1E (functional) [H72532], metallothionein 1X[BF130769], methylmalonate-semialdehyde dehydrogenase [BG743099], minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin) [BG491883], mucin 5, subtypes A and C, tracheobronchial/gastric [AW867962], myeloid differentiation primary response gene (88) [AW965179], myosin X [AU151619], non-metastatic cells 1, protein [NM23A] expressed in [BG753664], osteoblast specific factor 2 (fasciclin I-like) [N71912], pancreatitis-associated protein [NM002580], peptidylprolyl isomerase F (cyclophilin F) [AL531948], period (Drosophila) homolog 1 [BE615751], phosphatidic acid phosphatase type 2B [AW131816], phosphoinositide-3-kinase, class 2, gamma polypeptide [BG196286], phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) [BE884737], pituitary tumor-transforming 1 [AW957275], platelet-derived growth factor receptor, alpha polypeptide [AW887370], plexin B2 [BC004542], potassium inwardly-rectifying channel, subfamily J, member 15 [BG288548], predicted using Genefinder~contains similarity to Pfam domain: PF00465 (Iron-containing alcohol dehydrogenases), Score=177.7, E-value=1.9e-50, N=2~cDNA EST EMBL:Z14517 comes from this gene; cDNA EST yk18d4.3 comes from this gene~c [CAA21631], proprotein convertase subtilisin/kexin type 7 [BG820292], prostate stem cell antigen (AJ297436), protein disulfide isomerase [NM006849], protein tyrosine phosphatase, receptor-type, Z polypeptide 1 [BI488535], patative [BAB32258], RAB27A, member SAS oncogene family [AL120794] RAD21 (S. pombe) homolog [BF696386], RAP1, GTPase activating protein 1 [M64788], Ras homolog enriched in brain 2 [AW519065], RecQ protein-like 5 [AI123482], regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein) [BI713022], replication factor C (activator 1) 2 (40 ku) [BE295474], replication factor C (activator 1) 5 (36.5 ku) [AL525427], ribonuclease, RNase A family, 1 (pancreatic) [BI596306], ribosomal protein L12 [BG471683], ribosomal protein S10 [BC004334], ribosomal protein S12 [AA314429], ribosomal protein S15a [BG285655], ribosomal protein S20 [BG684583], S100 calcium-binding protein P [AI148603], pleckstrin homology domain containing, family E (with leucine rich repeats) member 1 [AB011178], selenium binding protein 1 [BC009084], serine/threonine kinase 15 [AI038260], Sjogren syndrome antigen B (autoantigen La) [AA479280], small nuclear ribonucleoprotein D2 polypeptide (16.5 ku) [BM015197], sodium channel, nonvoltage-gated 1 alpha [BI160595], sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) [BI763841], sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) [AI683977], somatostatin [BI713744], stem-loop (histone) binding protein [AW150631], trefoil factor 2 (spasmolytic protein 1) [BI517365], tumor necrosis factor (ligand) superfamily, member 13BG [272792], UDP-glucose ceramide glucosyltransferase [AI609116], vaccinia related kinase 1 [AA312869], v-akt murine thymoma viral oncogene homolog 2 [AU130605], vascular cell adhesion molecule 1 [AL037837]