Pyrrolidine dithiocarbamate reduces ischemia-reperfusion injury of the small intestine

Table 1 Systemic hemodynamic parameters in three experimental groups at baseline, 5 min before, at the end of 30 min ischemia and at 1 and 2 h post-reperfusion

Hemodynamic	Baseline	End of ischemia	1 h of reperfusion	2 h of reperfusion	P values
parameters
Heart rate (BPM)
Sham	250±5	252±3	240±8	230±10	>0.05
IR	251±2	252±2	220±4	227±12	>0.05
PDTC	252±3	251±3	240±10	232±7	>0.05
SaO2 (%)
Sham	98±2	95±2	94±3	95±2	>0.05
IR	98±1	95±2	97±2	95±3	>0.05
PDTC	98±1	96±3	93±1	96±3	>0.05
MABP (mmHg)
Sham	83±6	76± 5	74±6	78±8	>0.05
IR	90±3	108±5b	81±3	72±5	<0.01
PDTC	87±5	107±5b	79±4	73±6	<0.01

Values are expressed as mean±SE of six animals in each group. SaO_2: arterial oxygen saturation; MABP: mean arterial blood pressure.

^bP<0.01 vs baseline.