Reperfusion injury after critical intestinal ischemia and its correction with perfluorochemical emulsion "perftoran"

Table 1 Changes in the structure of rat's mucosal layer after 90 min of partial intestinal ischemia (mean±SD)

Groups	Subgroups	Morphometric indexes
	(number of sections)	Height of number of safety of degree byvilli, μm crypts epithelium (%) Chiu scale
Intact	(n = 13)	497±25	143±16	100	0
Ischemia (90 min)	(n = 8)	524±16	135±44	100	II–III
Ischemia (90 min)	IA (n = 5)	200±11a	66±16	63±18	III
Reperfusion (90 min)	IB (n = 5)	152±20	73±30	56±27	IV
Ischemia (90 min)	IA (n = 8)	304±8a	77±27a	70±19a	III
Reperfusion (24 h)	IB (n = 9)	168±28	27±33	17±20	IV–V

^aP<0.05 vs subgroups IA (with PF) and IB (control).

Table 2 Changes in the structure of rat's mucosal layer after 90 min of global intestinal ischemia (mean±SD)

Groups	Subgroups	Morphometric indexes
	(number of sections)	Height of number of safety ofdegree by villi, μm cryptsepithelium (%) Chiu scale
Intact	(n = 2)	525±19	125±24	100	0
Ischemia (90 min)	IIA (n = 3)	326±28	129±12	100	III
Ischemia (90 min)	IIB (n = 7)	312±18	104±13	90±10	III
Reperfusion (90 min)	IIA (n = 20)	296±9	118±9	97±3	III
Ischemia (90 min)	IIB (n = 24)	285±9	107±6	91±4	III

There were no significant differences between subgroups 2A (with PF) and B (control).