Hepatitis E virus chimeric DNA vaccine elicits immunologic response in mice

Table 1 Protocol of DNA injection

Group	Mice (n)	Immunogen	Time of injection (wk)
1	8	Saline	0 3 6
2	8	pcDNA3(100 μg/100 μL)	0 3 6
3	8	pcHEV23(100 μg/100 μL)	0 3 6
4	8	pcHEV23(200 μg/100 μL)	0 3 6

Table 2 Anti-HEV IgG titers after the third injection (mean±SD)

Group	1	2	3	4
Mean±SD	0.116±0.009b	0.210±0.028b	0.353±0.085b	0.336±0.066b

^bP<0.01 vs control.

Table 3 Result of assay of T-cell proliferation (mean±SD)

Group	1	2	3	4
	0.787±0.12b	1.54±0.25b	3.1±0.49b	2.85±0.59b

^bP<0.01 vs control.